Gallbladder Mucocele Formation is Associated with Proteinuria

CHF Grant 01986: Profiling the Metabolic and Lipid Imbalances that are Causative of Gallbladder Disease in Dogs

Publication: Lindaberry, C., Vaden, S., Aicher, K. M., Seiler, G., Robertson, J., Cianciolo, R., Yang, C., & Gookin, J. L. (2021). Proteinuria in dogs with gallbladder mucocele formation: A retrospective case control study. Journal of Veterinary Internal Medicine. 2021; 1– 9. https://doi.org/10.1111/jvim.16051

What can we learn?
Research is ongoing to uncover the metabolic disturbances that lead to gallbladder mucocele formation in dogs. Since mucocele formation is associated with several conditions (Cushing’s Disease, hyperlipidemia, and pancreatitis) that are associated with proteinuria, investigators explored the possibility of a direct relationship between gallbladder mucocele formation and proteinuria. A retrospective case control study documented that mucocele formation is associated with proteinuria in dogs.

Conclusion:
Dogs with gallbladder mucocele should be evaluated for proteinuria and treated accordingly to improve clinical outcomes. Occult gallbladder mucocele formation should be considered a possible cause for proteinuria in dogs.