Cardiac Biomarkers in Acute Pancreatitis

CHF Grant 02861-A: Cardiovascular Complications of Acute Pancreatitis in Dogs

Publication: Cridge, H, Langlois, DK, Steiner, JM, Sanders, RA. Cardiovascular abnormalities in dogs with acute pancreatitis. J Vet Intern Med. 2022; 1- 9. doi:10.1111/jvim.16597.

What can we learn?
To assess the prevalence and clinical importance of cardiac abnormalities in dogs with acute pancreatitis, investigators measured high sensitivity troponin I (TnIH) or cardiac troponin I (cTnI) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels in serum samples from 72 dogs with clinical signs of pancreatitis and high Spec cPL concentrations. Twelve additional dogs had echocardiography and Holter monitoring performed. Higher troponin levels were found in dogs with higher Spec cPL concentrations, but cardiac biomarkers were not associated with disease severity.

Conclusion:
Myocardial injury is reportedly common in dogs with acute pancreatitis. However, since clinical consequences were uncommon in the cohort studied here, cardiac biomarkers should be interpreted with caution in dogs with this disease.