Ophthalmology Grants

Through the Ophthalmology Research Program Area, the AKC Canine Health Foundation will support basic and clinical research into diseases of the canine eye. Areas of emphasis within this program area include genetics, mechanisms of disease, pathology and molecular interactions important to the eye, and clinical application of research findings to the prevention, diagnosis, and treatment of diseases affecting the eye and visual system.

Active Grants:

 02696 Efficacy and Safety of Netarsudil for Canine Corneal Endothelial Dystrophy
 02572-MOU Characterization of Retinal Phenotypes and their Association with RPGRIP1 and Modifiers in English Springer Spaniels
 02608 Identification of Genetic Risk Factors for Primary Closed Angle Glaucoma and Pectinate Ligament Abnormality in the Basset Hound
 02569-MOU Development of a Polygenic Risk Model for Pigmentary Uveitis in Golden Retrievers
 02590-A Histologic characterization of Golden Retriever Pigmentary Uveitis
 02432-A Tears as a Source of Biomarkers for Dry Eye in the Dog
 2517 Genetics of Primary Angle Closure Glaucoma in the Siberian Husky
 02403-MOU Microphthalmia and Delayed Growth Syndrome in the Portuguese Water Dog
 02332-A Identification of Mutations for Primary Lens Luxation in Multiple Dog Breeds
 2336 Genetics of Primary Angle Closure Glaucoma in American Cocker Spaniels

Previously Awarded Grants:

 2340 Clinical and Genetic Background of Progressive Retinal Atrophy in Miniature Schnauzers
 2061 Emergence of Pigmentary Uveitis as a Potential Cause of Cataracts and Glaucoma
 02243-A Genomic Profiling of Canine Corneal Endothelial Dystrophy
 02105-A The Genetics of Keratoconjunctivitis Sicca in West Highland White Terrier
 2057 Identification of the Genetic Cause of Corneal Ulcers
 02145-A Prevention of Glaucoma and Goniodysgenesis through Genetic Profiling of Disease
 02146-A Development of a Novel Drug Delivery System to Prevent Vision Loss in Canine Cataract Patients
 1594 Identifying the Genes Associated with Glaucoma
 01727-A Emergence of Pigmentary Uveitis as a Potential Cause of Cataracts and Glaucoma
 01874-A Identifying the Genes That Confer Risk for Development of Cataracts
 1612 Regulation of Inflammation to Prevent Cataract Surgery Complications
 01670-A Pinpointing the causal mutation(s) underlying a genome-wide association signal for hereditary cataract in Northern breeds
 1137 Eradication of Cairn Terrier Ocular Melanosis
 972 Identification of Mutations Associated with Hereditary Cataracts in Northern Breeds
 747 The Mapping and Characterization of Mutations Responsible for Canine Glaucoma
 763 Capsular Tension Ring Effect on Canine Lens Epithelial Migration and Post-Operative Lens Capsule Opacification
 642 Investigation of the Genetic Mutations Underlying Progressive Retinal Atrophy
 00985-A In vivo Effects of Tetracycline on Canine Refractory Ulcers
 00881-A Identifying the Mutation Causing Lens Luxation in the Tibetan Terrier
 01012-A Genetic Studies in Chronic Superficial Keratitis in German Shepherd Dogs
 00997-A Virological Survey of Dogs with Idiopathic Conjunctivitis
 00903-A Candidate Gene Investigation of Cairn Terrier Ocular Melanosis
 00866-A Phenotypic Characterization Using Electroretinography in Hereditary Retinal Degeneration of English Springer Spaniels
 00726-A Pharmacokinetics of Topically Applied Ciprofloxacin in Canine Tears
 00567-A Mapping the Genetic Lesion of Primary Lens Luxation in Lancashire Heelers, Miniature Bull Terriers and Other Terrier Breeds

The AKC Canine Health Foundation funds research in 23 different Research Program Areas for the health of all dogs. These program areas enable the Foundation to create depth in our research portfolio and help us to be responsive to the health concerns of our constituents.


Help Future Generations of Dogs

Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.

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