1401: Identification of Candidate Genes Causing Hereditary Myopathy in Labrador Retriever Dogs
Grant Status: Closed
Project SummaryThis study helped redirect the efforts to find the gene responsible for hereditary myopathy in Labrador Retrievers. In studying tissue samples from the muscles of affected dogs to try to identify proteins that are unique to dogs with this autosomal recessive muscular disease, researchers discovered that these proteins are identical in normal and affected dogs. Research efforts have turned to molecular studies to find the gene. Researchers have nearly completed sequencing a gene that they suspect is responsible for the disease (selected based on a similar disease in humans). Once future funding allows the sequencing to be completed, researchers hope to find a mutation on the gene that will allow the development of an unequivocal genetic test to identify carriers of the disease.
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.