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Immune Complex-Mediated Glomerulonephritis in Dogs

March 25, 2025

Photo of Dr. Mary Nabity


Chronic kidney disease is a significant cause of illness and death in dogs and is often caused by glomerular diseases. A specific category of glomerular disease called immune complex-mediated glomerulonephritis (ICGN) accounts for approximately 50% of dogs that have a kidney biopsy due to suspicion of glomerular disease.

Currently, ICGN can only be diagnosed with evaluation of a kidney biopsy, as there are no available biomarkers that can accurately identify this category of glomerular disease. Ongoing research is exploring potential biomarkers that could allow veterinarians to non-invasively diagnose ICGN. This would allow for more confidence in the appropriate treatment of dogs with this type of kidney disease, particularly in patients that are not good candidates for a kidney biopsy.

In this webinar, we will review the various diagnostic categories of glomerular disease in dogs and learn about potential new tools for differentiating immune complex-mediated glomerulonephritis from other forms of kidney disease.

Original Air Date: Tuesday, March 25, 2025
Speaker: Mary Nabity, DVM, PhD


CLICK HERE TO WATCH ON DEMAND


This program has been RACE approved for 1 hour of continuing education credit in jurisdictions that recognize RACE approval.

Learn more about Dr. Nabity’s CHF-funded research:
03281-MOU: Kidney Disease in Shetland Sheepdogs
03106: Clinical Validation of Urinary miR-126 as a Marker of Immune Complex- Mediated Glomerulonephritis in Dogs
02066: Identification of Novel Biomarkers and Therapeutic Targets for Chronic Kidney Disease in Dogs
02152: Translation of MicroRNA into an Early Diagnostic Test for Chronic Kidney Disease

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