03474-A: Engineering Cytokine-Receptor–Enhanced CAR T Cells to Achieve Long-Term Persistence and Durable Remission in Canine B-Cell Lymphoma
This research focuses on canine lymphoma, a common cancer with tens of thousands of new cases each year in the United States. Standard chemotherapy often works at first, but the disease frequently returns within 12 months, so better, longer lasting options are urgently needed. A new treatment called chimeric antigen receptor T cell (CAR-T) therapy […]
03526-A: Identification of a tumor cell associated protein target and development of a therapeutic nanobody for the treatment of canine B cell lymphoma.
This research focuses on a type of white blood cell cancer in dogs, called B-cell lymphoma, a frequently occurring cancer that affects several lymph nodes throughout the body (becoming swollen and painful) and is currently uncurable. Our goal is to develop a new immunotherapy by finding a druggable target unique to these lymphoma cells and […]