02945-MOU: Understanding the Genetic Basis of Addison’s Disease in Portuguese Water Dogs
Addison’s disease (AD) is a common, life-threatening disorder in dogs characterized by the immune-mediated destruction of portions of the adrenal gland. This damage prevents the adrenal gland from synthesizing hormones that are necessary for normal cell metabolism, kidney function, and maintenance of the immune system. Dogs with AD are also highly predisposed to succumbing to […]
02417-A: Serum total histones in dogs with acute pancreatitis, their association with laboratory findings, markers of inflammation and outcome: a prospective longitudinal study
Acute pancreatitis (AP) is a common, potentially fatal, inflammatory disease in dogs. Miniature Schnauzers and several Terrier and non-sporting breeds are predisposed to develop AP. The spectrum of clinical signs greatly varies, from transient inappetence in mild cases, to intractable gastro-intestinal signs and jaundice in severe ones. The result of aberrant activation of pancreatic digestive […]
02686-A: Pattern of Thyroid Function Tests during Recovery from Acute Nonthyroidal Illness
Hypothyroidism is the most common endocrine disease in dogs. A diagnosis of hypothyroidism relies on finding both appropriate clinical signs and low thyroid hormone levels. Unfortunately, other illnesses can suppress thyroid hormone levels and result in a misdiagnosis. This phenomenon of low thyroid hormone levels caused by a disease not involving the thyroid gland is […]
02475-A: Effect of Periodontal Treatment on Glycemic Control in Canine Diabetic Patients: A Prospective, Clinical Study
Diabetes mellitus (DM) is a common endocrine disorder in dogs, with a strong breed disposition. The disease is associated with significant morbidity and death when left untreated, and tight control of blood glucose levels is crucial in avoiding the harmful effects of long-standing hyperglycemia. Insulin administration, appropriate diet, and treatment of concurrent diseases which interfere […]
02948-A: Effect of Glycemic Control on the Onset of Cataract Development in Diabetic Dogs
Diabetes mellitus is a common endocrine disorder in dogs. Its most common long-term complication is cataract formation, occurring in about half of the dogs within six months of diagnosis. Diabetic cataracts typically develop quickly, causing blindness and requiring expensive surgery to restore vision. It is generally assumed that tight control of blood glucose levels delays […]
Monitoring Subclinical Thyroid Disease
Introduction Hypothyroidism is one of the most common hormonal disorders in dogs, but diagnosing it accurately can be tricky, especially when early signs are subtle or hidden. A new long-term study funded by the AKC Canine Health Foundation sheds light on a condition called subclinical thyroiditis, helping dog owners and veterinarians better understand which dogs […]
Better Testing for Acute Pancreatitis in Dogs
Introduction Acute pancreatitis is a serious and sometimes life-threatening condition that can affect dogs suddenly and without warning. It causes inflammation in the pancreas, an organ essential for digestion and blood sugar regulation. Recent research funded by the AKC Canine Health Foundation explored whether a specific protein called histones could help predict how severe the […]
The Complex Genetics of Diabetes Mellitus in Australian Terriers
Dogs can suffer from diabetes mellitus, which resembles Type I or insulin-dependent diabetes in humans. In this condition, the pancreas does not make any insulin, the hormone needed to move sugar from the bloodstream into the body’s cells that use it as fuel. Insulin must be given as treatment for the body to function. Since […]
Developing More Accurate Tests for the Diagnosis of Canine Hypothyroidism
Author: Sharon M. Albright, DVM CCRT Canine hypothyroidism is a common endocrine disease that results in symptoms such as lethargy, weight gain, and skin and coat problems due to decreased thyroid hormone production. It is seen in medium to large-size dogs of both sexes and is usually diagnosed between 4-10 years of age. Thyroid hormone […]