Research Aims to Improve Quality of Life for Dogs with Epilepsy
Just like people, dogs can suffer from epilepsy. This seizure disorder is characterized by uncontrolled electrical activity in the brain resulting in abnormal movements,
Comparison of clorazepate and levetiracetam as pulse therapy for the in-home management of cluster seizures in dogs with idiopathic epilepsy: a pilot study
We are seeking dogs with idiopathic epilepsy that experience cluster seizures for a new study led by Drs. Karen Muñana and Alejandra Mondino, evaluating pulse therapy for the in-home treatment of cluster seizures. Dogs will be recruited based on the following inclusion criteria: Dogs must not currently be prescribed an in-home emergency protocol that includes […]
Evidence for the Use of CBD to Treat Canine Idiopathic Epilepsy
Introduction If your dog suffers from epilepsy, you know how heartbreaking and unpredictable seizures can be. A new study funded by the AKC Canine Health Foundation (CHF) offers hope: cannabidiol (CBD) oil may help reduce seizure frequency in dogs with idiopathic epilepsy. This breakthrough research, conducted at Colorado State University, shows that CBD oil could […]
Prognostic Biomarkers for the Development of Drug Resistance in Dogs with Idiopathic Epilepsy
Idiopathic epilepsy is one of the most common brain diseases in dogs affecting between 0.6% and 5% of the general canine population. A genetic predisposition has been proven or is suspected in more than 20 breeds making genetic epilepsy a widespread condition among the entire canine population. Current treatments are associated with a high rate […]
The Genetics of Idiopathic Epilepsy in the Belgian Sheepdog and Belgian Tervuren
Introduction Idiopathic epilepsy is the most common medical neurologic disorder in dogs. It is defined as seizures with no identifiable cause. Despite appropriate anti-convulsant therapy, approximately 30% of affected dogs continue to have seizures. Because idiopathic epilepsy is more common in the Belgian Sheepdog and Belgian Tervuren, genetics are believed to play a role in […]
Assessment of Frequency of Seizures and Antiseizure Drug (ASD) Efficacy by Electroencephalography (EEG) for Dogs with Epilepsy
Epilepsy is the most common brain disease encountered in dogs. Epilepsy can be caused by several underlying problems responsible for the recurrent seizures seen in the disease. Accurate seizure control has an impact on the quality of life and survival time in epileptic dogs as well as on their caretaker’s quality of life. There is […]
Investigating Neuronal Network Connectivity in Dogs with Idiopathic Epilepsy using Functional Magnetic Resonance Imaging
Idiopathic epilepsy is the most common chronic neurological disease of dogs, but its cause remains poorly understood. There is a need to better understand the mechanism of disease in idiopathic epilepsy, if more effective management of the disease is to be achieved. Functional magnetic resonance imaging (fMRI) is a noninvasive technique to evaluate brain activity […]
A Dose Finding Study of Cannabidiol in Dogs with Idiopathic Epilepsy
Affecting approximately 5% of the canine population, idiopathic epilepsy is a widespread disease that is often frustrating and, at times, devastating to both dogs and their owners. About one third of dogs afflicted by idiopathic epilepsy are refractory to the standard drugs available to treat the disease. Therefore, finding an effective replacement or adjunctive medication […]