01898-A: Enhancing Diagnosis and Treatment of Cardiomyopathy through Identification of Biological Markers of Disease
Grant Status: Closed Grant Amount: $12,960 Suzanne M. Cunningham, DVM; Tufts University February 1, 2013 – January 31, 2015 Sponsor(s): American Bouvier des Flandres Club – Bouvier Health Foundation, Boston Terrier Club of America Breed(s): Boxer Research Program Area: Cardiology Donate to Support this Research Program Area Project Summary The development of blood-based cardiac biomarkers […]
0002002: Evaluation of the Clinical Outcome of Asymptomatic Adult Boxers with Ventricular Arrythmias Over a Four-Year Period
Heart disease in the Boxer was initially documented in the 1980s and referred to as a Boxer cardiomyopathy. More recent studies have confirmed that this disease is inherited and is primarily characterized by disturbances in the cardiac electrical system, fainting episodes and sudden death. The inherited nature of the disease has led to increased interest […]
01490-A: Evaluation of Aurora kinase inhibitors in canine lymphoma in vitro
Grant Status: Closed Grant Amount: $11,538 Keijiro Shiomitsu, D.V.M.; Louisiana State University June 1, 2010 – May 31, 2011 Sponsor(s): American German Shepherd Dog Charitable Foundation, Inc., Bernese Mountain Dog Club of America, English Setter Association of America, Inc., Golden Retriever Foundation Breed(s): -All Dogs Research Program Area: Oncology – Lymphoma Donate to Support this […]
01726-A: Identifying Growth Factors That Promote the Spread of Osteosarcoma
Grant Status: Closed Grant Amount: $11,135 Stuart Helfand, DVM; Oregon State University April 1, 2012 – September 30, 2013 Sponsor(s): Golden Retriever Foundation Breed(s): Irish Wolfhound Research Program Area: Oncology – Osteosarcoma Donate to Support this Research Program Area Project Summary The ideal cancer treatment would destroy all cancer cells at the site where the […]
01271B: Mapping of Additional Genes Associated with Canine Degenerative Myelopathy
Grant Status: Closed Grant Amount: $64,134 Joan R. Coates, DVM; University of Missouri, Columbia January 1, 2010 – March 31, 2012 Sponsor(s): Clumber Spaniel Club of America, English Cocker Spaniel Club of America, Old English Sheepdog Club of America, Saluki Health Research, Inc., Tibetan Terrier Club of America/Tibetan Terrier Health & Welfare Foundation Breed(s): Pembroke […]
01585: Evaluating a Safer, Less Toxic Radiation Therapy in the Treatment of Lymphoma
Grant Status: Closed Grant Amount: $93,140 Michael A. Deveau, DVM, MS; Texas A&M Research Foundation January 1, 2012 – June 30, 2014 Sponsor(s): American Foxhound Club, American German Shepherd Dog Charitable Foundation, Inc., American Spaniel Club Foundation, Clumber Spaniel Club of America, English Setter Association of America, Inc., Keeshond Anonymous Fund, Pembroke Welsh Corgi Club […]
00873-A: Preliminary Disease Gene Mapping of Juvenile Renal Dysplasia in the Boxer Dog
Juvenile Renal Dysplasia (JRD) affects young dogs of several breeds. Affected dogs show increased amount of urination (unconcentrated urine), increased intake of water, vomiting, lethargy, and weight loss, eventually leading to kidney failure between age of 6 weeks and 4 years. A particularly high prevalence in certain breeds, such as Lhasa Apso, Shih Tzu and […]
00228T: A Comparative Evaluation of the Concealed and Overt Forms of Arrhythmogenic Right Ventricular Cardiomyopathy: Risk Factors Associated with the Development of Symptoms in Dogs with Arrhythmogenic Right Ventricular Cardiomyopathy
The clinical syndrome characterized by ventricular arrhythmias, collapsing episodes, sudden cardiac death and, sometimes, heart failure in the Boxer was previously referred to as Boxer cardiomyopathy. More recent studied have demonstrated striking similarities, including the inheritance, to a human disease called Arrhythmogenic Right Venticular Cardiomyopathy (ARVC). The familial nature as well as the devastating outcome […]
01787: Clinical Advancement of a Cancer Vaccine in Dogs
Canine lymphoma is the most common blood-based cancer in dogs with an estimated annual incidence of 30/100,000. Chemotherapy induces remission in 75-85% of patients; however, the majority of patients relapse with drug-resistant lymphoma within 8-10 months of diagnosis and most dogs die of their disease shortly thereafter. Cell-based vaccine strategies that stimulate anti-tumor immunity have […]
01689-A: Increasing the Effectiveness of Radiation Therapy in Treatment of Mast Cell Tumors
Canine mast cell tumors are the most common cutaneous malignant tumors in dogs. Histologic grades, I, II, and III, provide very useful information because they are indicative of a patient’s prognosis. Treatment options depend on negative prognostic factors, but in general surgery and radiation therapy are very effective. Chemotherapy could be applied if the patient […]