Celebrating the Breakthroughs Shaping the Future of Canine Health. Meet the 2025 Canine Health Discovery Award Finalists.

Donate
iconamoon_search-thin

Advancing Canine Health through Peer-Reviewed Publications

Scientific peer-reviewed publications are a cornerstone of advancing canine health. At the AKC Canine Health Foundation (CHF), research investment success is measured, in part, by the quality and impact of the peer-reviewed studies they produce.

These publications not only validate the rigor and credibility of the research supported by the CHF but also contribute to the global body of scientific knowledge, driving innovation and improving the lives of all dogs.

Publications

Common variants in the CPT1A gene are associated with cataracts in Northern breeds of domestic dog
CHF Grant ID(s): 01670-A, 972
Program Area: Eye Health
Investigator(s): Ricketts, Sally L.; Ahonen, Saija; Pettitt, Louise; Freyer, Jamie; Ellis, Stuart; Jenkins, Christopher A.; Kaukonen, Maria; Boursnell, Mike; Schofield, Ellen; Forman, Oliver P.; Lohi, Hannes; Mellersh, Cathryn S.
Dextromethorphan phenotyping of healthy pet dogs reveals breed-associated differences in cytochrome P450 2D15–mediated drug metabolism
CHF Grant ID(s): 2242, 2529
Program Area: Digestive Health, General Health & Wellness
Investigator(s): Jimenez, Tania Perez; Trostle, Mara; Zhu, Zhaohui; Martinez, Stephanie; Court, Michael H.
Development of a web-based tool to assess daily rating of perceived exertion in agility dogs
CHF Grant ID(s): 03180-A
Program Area: Muscles, Bones, & Joints
Investigator(s): Sellon, Debra; Shoben, Abigail; Markley, Arielle; McFarlane, Dianne; Marcellin-Little, Denis
Autophagy regulates cellular senescence by mediating the degradation of CDKN1A/p21 and CDKN2A/p16 through SQSTM1/p62-mediated selective autophagy in myxomatous mitral valve degeneration
CHF Grant ID(s): 3101-A
Program Area: Heart Health
Investigator(s): Tang, Qiyu; Tang, Keyi; Markby, Greg R.; Parys, Maciej; Phadwal, Kanchan; MacRae, Vicky E; Corcoran, Brendan M.
Study aims for DNA test to reduce glaucoma in Entlebucher Mountain Dogs
CHF Grant ID(s): 2963
Program Area: Eye Health
Investigator(s): Levine, Jonathan M.
Changes in thyroid hormone concentrations over time in dogs with autoimmune thyroiditis
CHF Grant ID(s): 02298, 02659
Program Area: Hormonal Health
Investigator(s): Egbert, Rebecca J.; Basu, Puja; Refsal, Kent R.; Petroff, Margaret G.; Petroff, Brian K.