Celebrating the Breakthroughs Shaping the Future of Canine Health. Meet the 2025 Canine Health Discovery Award Finalists.

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Advancing Canine Health through Peer-Reviewed Publications

Scientific peer-reviewed publications are a cornerstone of advancing canine health. At the AKC Canine Health Foundation (CHF), research investment success is measured, in part, by the quality and impact of the peer-reviewed studies they produce.

These publications not only validate the rigor and credibility of the research supported by the CHF but also contribute to the global body of scientific knowledge, driving innovation and improving the lives of all dogs.

Publications

Immunologic Effects of Stereotactic Body Radiotherapy in Dogs with Spontaneous Tumors and the Impact of Intratumoral OX40/TLR Agonist Immunotherapy
CHF Grant ID(s): 02487
Program Area: General Cancer
Investigator(s): Boss, Mary-Keara; Watts, Remy; Harrison, Lauren G.; Hopkins, Sophie; Chow, Lyndah; Trageser, Erin; Easton, Carina; LaRue, Susan M.; Regan, Daniel; Dewhirst, Mark W.; Dow, Steven
Genome wide exploration of the methylome in aggressive B-cell lymphoma in Golden Retrievers reveals a conserved hypermethylome
Investigator(s): Chu, Shirley; Avery, Anne; Yoshimoto, Janna; Bryan, Jeffrey N.
Congenital idiopathic megaesophagus in the German shepherd dog is a sex-differentiated trait and is associated with an intronic variable number tandem repeat in Melanin-Concentrating Hormone Receptor 2
CHF Grant ID(s): 02709, 02654-E
Program Area: Digestive Health
Investigator(s): Bell, Sarah M.; Evans, Jacquelyn M.; Evans, Katy M.; Tsai, Kate L.; Noorai, Rooksana E.; Famula, Thomas R.; Holle, Dolores M.; Clark, Leigh Anne
Genome wide exploration of the methylome in aggressive B-cell lymphoma in Golden Retrievers reveals a conserved hypermethylome
CHF Grant ID(s): 01918-G
Program Area: Lymphoma
Investigator(s): Chu, Shirley; Avery, Anne; Yoshimoto, Janna; Bryan, Jeffrey N.
Differential T-cell responses in dogs with meningoencephalomyelitis of unknown origin compared to healthy controls
CHF Grant ID(s): 02452
Program Area: Nervous System Health
Investigator(s): Barber, Renee; Barber, James
Case Report: Disorder of Sexual Development in a Chinese Crested Dog With XX/XY Leukocyte Chimerism and Mixed Cell Testicular Tumors
CHF Grant ID(s): 02846-E, 2021 Theriogenology Residency Program
Program Area: Theriogenology Residencies
Investigator(s): Schwartz, Rebecca; Sugai, Nicole J.; Eden, Kristin; Castaneda, Caitlin; Jevit, Matthew; Raudsepp, Terje; Cecere, Julie T.