Hormonal Health Research
The AKC Canine Health Foundation (CHF) supports research into diseases of the endocrine system, focusing on genetic causes, stem cell therapies, novel diagnostics, and potential treatments for hormonal disorders.
Why We Focus on Hormonal Health
Hormonal diseases can be life-threatening and may require lifelong management. These include conditions such as diabetes, hypothyroidism, and Addison’s disease. By understanding the causes and mechanisms behind these conditions, we can improve early diagnosis and develop more effective treatments, enhancing the quality of life for affected dogs.
Research Grants
Hormonal Health ● $19,634.00
03387-A: Luteinizing Hormone Receptor Activation Interferes with Canine Thyroid Hormone Secretion in Response to Thyroid Stimulating Hormone In Vitro
Breed(s): All Dogs
Researcher(s): Dr. Michelle Ann Kutzler, DVM, PhD
Eye Health, Hormonal Health ● $15,000
02948-A: Effect of Glycemic Control on the Onset of Cataract Development in Diabetic Dogs
Breed(s): All Dogs
Researcher(s): Michal Mazaki-Tovi, DVM
Hormonal Health ● $207,381
02945-MOU: Understanding the Genetic Basis of Addison’s Disease in Portuguese Water Dogs
Breed(s): Portuguese Water Dog
Researcher(s): Steven G Friedenberg, DVM, PhD
Sponsor(s): Portuguese Water Dog Foundation
Hormonal Health ● $106,939
02875: Canine Pituitary Adenoma Organoids (CaPitO) as an in vitro Model for Canine Cushing’s Disease
Breed(s): All Dogs
Researcher(s): Karin Sanders, DVM, PhD
Sponsor(s): American Miniature Schnauzer Club, Health & Rescue Foundation of the Petit Basset Griffon Vendéen Club of America, Versatility in Poodles, Inc.
Hormonal Health ● $14,999
02850-A: Potential Reduction of Systemic and Pancreatic Inflammation using Fenofibrate in Diabetic Dogs
Breed(s): All Dogs
Researcher(s): Chen Gilor, DVM, PhD
Sponsor(s): American Miniature Schnauzer Club, Health & Rescue Foundation of the Petit Basset Griffon Vendéen Club of America
Hormonal Health ● $13,792
02686-A: Pattern of Thyroid Function Tests during Recovery from Acute Nonthyroidal Illness
Breed(s): All Dogs
Researcher(s): Timothy Bolton, DVM
Sponsor(s): Portuguese Water Dog Foundation
Hormonal Health ● $139,975
02659: Breed Specific Reference Ranges for Canine Thyroid Testing
Breed(s): Irish Setter, Rhodesian Ridgeback, Whippet
Researcher(s): Brian Petroff, DVM, PhD
Sponsor(s): Anatolian Shepherd Dog Club of America, Great Pyrenees Club of America, Rhodesian Ridgeback Charitable Foundation, Gordon Setter Club of America, Inc., Irish Setter Club of America Foundation, Vizsla Club of America Welfare Foundation
General Health & Wellness, Hormonal Health ● $14,970
02475-A: Effect of Periodontal Treatment on Glycemic Control in Canine Diabetic Patients: A Prospective, Clinical Study
Breed(s): Bichon Frise, Border Collie, Cairn Terrier, Cavalier King Charles Spaniel, Miniature Poodle, Miniature Schnauzer, Samoyed, Tibetan Terrier, West Highland White Terrier, Yorkshire Terrier
Researcher(s): Michal Mazaki-Tovi, DVM
Sponsor(s): Miniature Pinscher Club of America, Inc.
Hormonal Health ● $118,458
02488: Addison’s Disease and Symmetrical Lupoid Onychodystrophy in Bearded Collies Provide Common Ground for Identifying Susceptibility Loci Underlying Canine Autoimmune Disorders
Breed(s): Bearded Collie
Researcher(s): Anita M. Oberbauer, PhD
Sponsor(s): BEACON for Health, The Robert Alan Braley Rev Tr, Bearded Collie Club of America, Portuguese Water Dog Foundation
Hormonal Health ● $191,985
02428: Identifying the Disease-Defining Autoantibodies in Canine Addison’s Disease
Breed(s): English Cocker Spaniel, Portuguese Water Dog, Standard Poodle
Researcher(s): Steven G Friedenberg, DVM, PhD
Sponsor(s): English Cocker Spaniel Club of America Health and Rescue Organization, Havanese Club of America, Papillon Club of America, SCWTCA Endowment, Inc., University of Minnesota, Versatility in Poodles, Inc., American Boxer Charitable Foundation, Gordon Setter Club of America, Inc., National Beagle Club, Portuguese Water Dog Foundation
Hormonal Health ● $14,200
02417-A: Serum total histones in dogs with acute pancreatitis, their association with laboratory findings, markers of inflammation and outcome: a prospective longitudinal study
Breed(s): Miniature Schnauzer
Researcher(s): Ran Nivy, DVM
Sponsor(s): Pratt, Margaret W. Revocable Living Trust
Hormonal Health ● $14,900
02342-A: Molecular Analysis of Giant Schnauzer-Type Congenital Hypothyroidism
Breed(s): Giant Schnauzer
Researcher(s): John C. Fyfe, DVM, PhD
Sponsor(s): The Robert Alan Braley Rev Tr, Orthopedic Foundation for Animals, Portuguese Water Dog Foundation
Hormonal Health ● $14,435
02366-A: Individualization of Pharmacological Interventions in Diabetic Dogs
Breed(s): Miniature Schnauzer
Researcher(s): Nicolas Villarino, Med.Vet., DVSc, PhD
Hormonal Health ● $35,630
02298-MOU: Using OFA Testing to Assess Progression of Canine Autoimmune Thyroiditis
Breed(s): All Dogs
Researcher(s): Brian Petroff, DVM, PhD
Sponsor(s): Orthopedic Foundation for Animals
Hormonal Health ● $48,195
02138: Development of Accurate Diagnostic Tests for Canine Hypothyroidism
Breed(s): All Dogs
Researcher(s): Jan A Mol, PhD
Sponsor(s): National Shiba Club of America, Staffordshire Terrier Club of America, Inc., Chow Chow Club, Inc., English Setter Association of America, Inc., Versatility in Poodles, Inc., American Bloodhound Club, Collie Health Foundation, Gordon Setter Club of America, Inc.
Join Us in Advancing
Canine Health
With more than $2.1 million invested in hormonal health studies, your support helps fund research that aims to improve the diagnosis, treatment, and management of endocrine disorders in dogs.
