Bone Cancer Research
The AKC Canine Health Foundation (CHF) supports research into osteosarcoma, the most common bone cancer in dogs. Our goal is to find new ways to improve the prognosis for dogs with this disease by studying its causes and looking for possible treatments.
Why We Focus on
Bone Cancer
Bone cancer, or osteosarcoma, is a very aggressive cancer that often spreads quickly, making it hard to treat. Unfortunately, even with the best therapies, the long-term outlook for dogs with osteosarcoma is often poor. Since this cancer in dogs is similar to bone cancer found in children, learning more about it in dogs may also help us understand and treat the disease in humans.
Research Grants
Bone Cancer ● $19,440.00
03400-A: FLASH radiation in dogs diagnosed with Osteosarcoma
Breed(s): All Dogs
Researcher(s): Nathaniel Van Asselt, DVM DACVR
Bone Cancer ● $165,592
03293: Foundational Studies for Translating FGFR Inhibition in Canine Osteosarcoma
Breed(s): All Dogs
Researcher(s): Marcella Massimini, PhD
Sponsor(s): Irish Setter Club of America Foundation
Bone Cancer ● $53,125.20
03285: Osteosarcoma metastasis-initiating cells
Breed(s): All Dogs
Researcher(s): Courtney R Schott, BSc, DVM, PhD, DACVP
Sponsor(s): Collie Health Foundation, Irish Setter Club of America Foundation
Bone Cancer ● $97,194
03262: Dual Energy Computed Tomography and Bone Resorption Markers in Dogs with Appendicular Osteosarcoma Treated with Stereotactic Body Radiation Therapy
Breed(s): All Dogs
Researcher(s): Tiffany W. Martin DVM, MS, DACVR
Sponsor(s): Irish Setter Club of America Foundation
Bone Cancer ● $20,000
03266-A: Development of a Novel Diagnostic Test for Canine Osteosarcoma Using Raman Spectroscopy
Breed(s): Great Dane, Greyhound, Irish Wolfhound, Leonberger, Rottweiler, Saint Bernard, Scottish Deerhound
Researcher(s): Terza Brostoff, DVM, PhD
Sponsor(s): Bull Terrier Club of America, Irish Setter Club of America Foundation
Bone Cancer ● $49,850.90
01660-T: Alternative Genetic Approaches for Identifying Canine Osteosarcoma Genes
Breed(s): Golden Retriever, Greyhound, Rottweiler
Researcher(s): Carlos E. Alvarez, PhD
Sponsor(s): Gordon Setter Club of America, Inc.
Bone Cancer ● $16,194
03095-A: Cell-Specific Expression of MicroRNAs in Primary and Metastatic Canine Osteosarcoma
Breed(s): All Dogs
Researcher(s): Geoffrey Wood, DVM, PhD
Sponsor(s): Irish Setter Club of Milwaukee, Inc., Mastiff Club of America, Gordon Setter Club of America, Inc., Irish Setter Club of America Foundation
Bone Cancer ● $460,620
03032-MOU: Early Detection of Canine Osteosarcoma
Breed(s): All Dogs
Researcher(s): Jamie Modiano, VMD, PhD
Sponsor(s): Great Dane Club of America Charitable Trust, Irish Wolfhound Foundation, Leonberger Health Foundation, Golden Retriever Foundation, Irish Setter Club of America Foundation, Rottweiler Health Foundation
Bone Cancer ● $161,903
03015: The Immune and Molecular Landscape of Canine Osteosarcoma at the Single-Cell Level
Breed(s): All Dogs
Researcher(s): Jaime F Modiano, VMD, PhD
Sponsor(s): Anatolian Shepherd Dog Club of America, Irish Wolfhound Foundation, Akita Club of America, Inc., Vizsla Club of America Welfare Foundation
Bone Cancer ● $54,918
03000: Characterizing the Immunomodulatory Response of Histotripsy in Canine Osteosarcoma
Breed(s): Greyhound, Irish Wolfhound, Scottish Deerhound
Researcher(s): Joanne Tuohy, DVM, PhD
Sponsor(s): English Setter Association of America, Inc., Irish Wolfhound Foundation, Golden Retriever Foundation, Irish Setter Club of America Foundation, Orthopedic Foundation for Animals
Bone Cancer ● $14,544
02991-A: Investigating Extracellular Crosstalk Between Canine Osteosarcoma and Macrophages
Breed(s): Boxer, Doberman Pinscher, German Shepherd Dog, Golden Retriever, Great Dane, Greyhound, Irish Setter, Irish Wolfhound, Labrador Retriever, Leonberger, Newfoundland, Rottweiler, Saint Bernard
Researcher(s): Erika Gruber, DVM, PhD
Sponsor(s): Rottweiler Health Foundation
Bone Cancer ● $25,380
02999: Evaluating Magnetic Resonance Imaging for Quantifying Histotripsy Ablation in Canine Osteosarcoma
Breed(s): Greyhound, Irish Wolfhound, Scottish Deerhound
Researcher(s): Joanne Tuohy, DVM, PhD
Sponsor(s): Irish Wolfhound Foundation, Golden Retriever Foundation
Bone Cancer, General Cancer ● $135,272
03019: Evaluation of a Targeted Anti αvβ3 Integrin Near-InfraRed (NIR-) Dye for Controlled Resection of Naturally Occurring Soft Tissue Sarcomas in Dogs
Breed(s): All Dogs
Researcher(s): Mirja Nolff, Dr. med. vet., DVM
Sponsor(s): Irish Setter Club of Milwaukee, Inc., Vizsla Club of America Welfare Foundation
Bone Cancer ● $94,605
02768: Defining the Functional Consequences and Therapeutic Vulnerability of Dystrophin Alterations in Canine Osteosarcoma
Breed(s): All Dogs
Researcher(s): Cheryl A. London, DVM, PhD
Sponsor(s): Great Pyrenees Club of America, Collie Health Foundation, Golden Retriever Foundation, Irish Setter Club of America Foundation
Bone Cancer ● $161,718
02782: Genetic Contribution to Early-onset Osteosarcoma
Breed(s): Afghan Hound, Doberman Pinscher, German Shepherd Dog, Golden Retriever, Great Dane, Greyhound, Irish Setter, Irish Wolfhound, Rottweiler, Saint Bernard, Scottish Deerhound
Researcher(s): Susannah Sample, DVM, MS, PhD
Sponsor(s): Irish Wolfhound Club of America, Inc., Irish Wolfhound Foundation
Join Us in Advancing
Canine Health
With over $2.9 million invested in bone cancer research, your support can help fund groundbreaking studies that aim to improve the lives of dogs battling this devastating disease.
