Investigating Volatile Organic Compounds as Potential Markers of Canine Hemangiosarcoma by Trained Bio-detection Dogs

Breed(s): -All Dogs
Sample Type: Blood Sample
Study Location: University of Pennsylvania, Penn Vet Working Dog Center
CHF-funded Grant: 03187

Canine hemangiosarcoma (HSA) is a cancer of the blood vessels of the liver, spleen and heart that is hard to diagnose until it is too late. Every two minutes, a dog dies from hemangiosarcoma. There is no screening test. New diagnostic tests are urgently needed to improve outcomes.

Researchers will train dogs to tell the difference between blood samples from dogs diagnosed with hemangiosarcoma versus dogs that are healthy or have other diseases. This research will aid the development of future techniques for diagnosing hemangiosarcoma.

Blood samples are needed from:

  • Dogs diagnosed with hemangiosarcoma
  • Healthy dogs that four year of age or older (any breed)
  • Dogs unwell with conditions other than hemangiosarcoma and are also four years of age or older

How to participate

  1. Confirm your dog is eligible based on the criteria above.
  2. Talk to Your Vet: Ask your vet clinic to register in the study by completing the information in this link: Please note, the only way to submit a sample is via a registered vet clinic.
  3. Set Up Appointment: Arrange a blood draw appointment at your registered clinic. If your dog is already scheduled for a blood draw for other reasons, inquire with your veterinarian if they can collect extra for this research.
  4. Sample Submission: Samples will be shipped by your veterinary clinic.

More Information


Contact Information:

Principal Investigator : Cynthia M. Otto, DVM, PhD DACVECC DACVSMR 

Phone: 215-898-2200

Help Future Generations of Dogs

Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.

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