Celebrating the Breakthroughs Shaping the Future of Canine Health. Meet the 2025 Canine Health Discovery Award Finalists.

03387-A: Luteinizing Hormone Receptor Activation Interferes with Canine Thyroid Hormone Secretion in Response to Thyroid Stimulating Hormone In Vitro

Hypothyroidism is the most common hormonal imbalance in dogs. It is a lifelong condition that significantly decreases quality of life and is associated with several other negative health outcomes including obesity, lethargy, and skin conditions. Airedale Terriers, Doberman Pinschers, Miniature Schnauzers, Pomeranians, Golden Retrievers, Cocker Spaniels, Shetland Sheepdogs, Irish Setters, Dachshunds, Tibetan Terriers, and Boxers […]

00687-A: Fluorescence-Activated Cell Sorting of Canine Pituitary Corticotroph Cells for Subsequent Microarray Analysis

Canine pituitary-dependent hyperadrenocorticism (PDH), or Cushing’s disease, is a severe and frequent endocrine disease in middle-aged to elderly dogs. Small breeds are over-represented and some breeds are at a higher risk of developing the disease than others. PDH is caused by an ACTH-producing pituitary adenoma with unknown pathogenesis. At the Department of Clinical Sciences of […]

0001657: Identification and Inheritance of DNA Markers for Addison’s Disease

The study found that Addison’s Disease (AD), the late-onset failure of adrenal gland function, is clearly inherited and appears to be regulated by a single gene that is inherited as an autosomal recessive. Researchers collected DNA samples and pedigrees from 390 Bearded Collies, 533 Standard Poodles and 167 Leonbergers. The samples were from both affected […]