02519: Prevalence of Bartonella spp. Infection in Dogs with Cardiac and Splenic Hemangiosarcomas within and between Geographic Locations
Splenic masses comprise ~50% of all canine splenic disease. Despite advances in imaging and pathologic definition, the etiology and medical relevance of splenic lesions in dogs are often ambiguous. While some splenic tumors are benign, approximately two-thirds are highly malignant and carry a poor prognosis. Hemangiosarcoma (HSA) accounts for the majority of canine malignant splenic […]
02234-MOU: A Novel Approach for Prevention of Canine Hemangiosarcoma
Hemangiosarcoma, an aggressive form of cancer in dogs, is the cause of death for one out of every five Golden Retrievers in the United States. Portuguese Water Dogs and Boxers also have an especially high risk for this disease which is devastating for all dogs. Hemangiosarcoma is incurable partly because the cancer is detected at […]
02864-A: Luteinizing Hormone Receptor Activation in Canine Hemangiosarcoma Cells
Hemangiosarcoma is an aggressive, silent cancer that sometimes snares its victims without any sign of illness. In the U.S., hemangiosarcoma is believed to be responsible for the deaths of tens of thousands of dogs each year. German Shepherd Dogs, Golden Retrievers, and Labrador Retrievers are most commonly affected but this cancer affects all dogs. While […]
02746-A: Evaluation of Serum miRNA as a Diagnostic Tool for Canine Splenic Hemangiosarcoma
Cancer is the leading cause of death in adult dogs, with hemangiosarcoma (HSA) being the most common tumor of the spleen. Affecting predominantly large-breed dogs, HSA is associated with a nearly 100% death rate with most dogs surviving 3-6 months with treatment. Other splenic masses occur in dogs which may have better prognoses; however, there […]
01925-A: Discovery of Novel Micro-Ribonucleic Acids for Diagnosis and Prognosis of Canine Hemangiosarcoma
Grant Status: Closed Grant Amount: $12,960 Bruce F Smith, VMD, PhD; Auburn University April 1, 2013 – May 31, 2014 Sponsor(s): Breed(s): Golden Retriever Research Program Area: Oncology – Hemangiosarcoma Donate to Support this Research Program Area Project Summary To date, all samples have been collected (5 normal spleens, 5 splenic nodular hyperplasias, 5 splenic […]
Investigating Volatile Organic Compounds as Potential Markers of Canine Hemangiosarcoma by Trained Bio-detection Dogs
Canine hemangiosarcoma (HSA) is a cancer of the blood vessels of the liver, spleen and heart that is hard to diagnose until it is too late. Every two minutes, a dog dies from hemangiosarcoma. There is no screening test. New diagnostic tests are urgently needed to improve outcomes. Researchers will train dogs to tell the […]
Towards Curative Outcomes in Canine Hemangiosarcoma
Canine hemangiosarcoma is the most aggressive cancer seen in all dogs, but disproportionately affects older, large breed dogs. A nation-wide clinical trial for 400 dogs with splenic hemangiosarcoma seeks to deliver curative outcomes for dogs with this disease. With collaboration from AKC Canine Health Foundation, dog-owning families from outside the geographical enactment of 30 Ethos […]
Researching New Treatments for Canine Hemangiosarcoma
Hemangiosarcoma is a deadly cancer of the cells that line blood vessels. It most commonly affects the spleen, heart, and skin of dogs. While skin tumors can often be cured by surgical removal, the prognosis for splenic hemangiosarcoma is poor due to microscopic spread of cancer cells throughout the body by the time it is […]