Celebrating the Breakthroughs Shaping the Future of Canine Health. Meet the 2025 Canine Health Discovery Award Finalists.

1 min read Grant Period: April 23, 1999 - April 22, 2000 Closed Grant

0001718: Molecular Genetic Basis of Epilepsy in Standard Schnauzers and English Springer Spaniels

Researchers in this study found a genetic marker they suspect might be responsible for epilepsy in Standard Schnauzers. After collecting DNA from Standard Schnauzers and English Springer Spaniels with epilepsy and their immediate relatives (in collaboration with researchers from the University of Minnesota) researchers screened the Standard Schnauzer families. Further research is necessary to verify whether the suspected marker they found is truly a linked marker. Researchers also looked at other areas of the canine genome, in segments of selected potassium and calcium channel genes. The goal of the study was to find the mutation responsible for causing epilepsy in Standard Schnauzers and English Springer Spaniels. If the mutation is found, a DNA marker could be produced that would allow breeders in those breeds to identify dogs that are carriers of the gene for epilepsy, and those that will develop the disorder. This project provided a foundation for ongoing research on epilepsy in these breeds, as well as in the Welsh Springer Spaniel.