This project sought to further the knowledge of the canine genome by developing methods to amplify DNA sequences and place them on the dog genome. The project was conducted in the early days of canine genomic research (it began in 1997) and the method that the researchers developed, combining randomly amplified polymorphic DNA (RAPDs) with florescent in situ hybridization (FISH) analysis to visually light up dog chromosomes, was awarded a patent in 1998. While additional methods have been developed, this research contributed to the body of knowledge that is allowing scientists to map the canine genome and identify genetic markers for diseases.


