03030-A: Evaluation of Serum C-reactive Protein as a Noninvasive Biomarker of Inflammation and Disease Severity in Dogs with Gallbladder Mucocele
In the last 20 years a condition called gallbladder mucocele has emerged as a very common disease of the liver in dogs. This disease is associated with the accumulation of congealed bile in the gallbladder that subsequently cannot empty properly into the intestine. The result of this is often irreversible damage to the gallbladder wall […]
01986: Profiling the Metabolic and Lipid Imbalances that are Causative of Gallbladder Disease in Dogs
The gallbladder mucocele (GBM) is one of the most common, poorly understood and deadliest biliary diseases of dogs. A GBM develops when the gallbladder secretes abnormal mucus that eventually obstructs or ruptures the gallbladder. GBM formation afflicts all dogs, but especially Shetland Sheepdogs, Miniature Schnauzers and Cocker Spaniels, and in general, dogs with disorders of […]
00441: Cloning of the pd Gene and Characterization of the Mutation Causing PRA in Miniature Schnauzers
Grant Status: Closed Grant Amount: $28,778.25 Gustavo D. Aguirre, VMD, PhD; Cornell University November 1, 1995 – January 14, 1999 Sponsor(s): Breed(s): Miniature Schnauzer Research Program Area: Ophthalmology Donate to Support this Research Program Area Publication(s) None at this time. Related Grants
02340: Clinical and Genetic Background of Progressive Retinal Atrophy in Miniature Schnauzers
Dogs may be affected with hereditary eye disorders, which cause severe vision impairment, and sometimes progress to complete blindness. One hereditary condition is progressive retinal atrophy (PRA), in which the lightâsensing receptors in the retina are lost, leading to complete blindness. Currently there are no treatment options for this disease. The development of genetic testing […]
02633: Validation and Diagnostic Performance of a Novel Monoclonal Antibody based Histoplasma Urine Immunoassay in Dogs with Histoplasmosis
Histoplasmosis is a severe disease caused by the fungus Histoplasma capsulatum that can be fatal to dogs. The fungus is found in soil and dust around the world and most commonly in the Midwestern, Southern, and Southeastern U.S. Dogs contract the disease when they inhale spores produced by the fungus in the environment. The most […]
02368: Identification of Mitral Valve Disease DNA variants in Miniature Schnauzers
Mitral valve degeneration is the most common heart disease in the dog and is particularly common in small breed dogs. Miniature Schnauzers are one of the most commonly affected breeds. Although some dogs live comfortably with the disease, many affected dogs die of congestive heart failure and sometimes sudden death due to rupture of a […]
02417-A: Serum total histones in dogs with acute pancreatitis, their association with laboratory findings, markers of inflammation and outcome: a prospective longitudinal study
Acute pancreatitis (AP) is a common, potentially fatal, inflammatory disease in dogs. Miniature Schnauzers and several Terrier and non-sporting breeds are predisposed to develop AP. The spectrum of clinical signs greatly varies, from transient inappetence in mild cases, to intractable gastro-intestinal signs and jaundice in severe ones. The result of aberrant activation of pancreatic digestive […]
02143-A: Development of a Novel Treatment for Intervertebral Disc Disease
Grant Status: Closed Grant Amount: $11,903 Gordon S. Mitchell; University of Wisconsin, Madison August 1, 2014 – January 31, 2016 Sponsor(s): Clumber Spaniel Health Foundation Breed(s): Dachshund Research Program Area: Neurology Donate to Support this Research Program Area Project Summary Subject recruitment was initiated upon receiving funding. Potential study subjects were identified through the electronic […]
02475-A: Effect of Periodontal Treatment on Glycemic Control in Canine Diabetic Patients: A Prospective, Clinical Study
Diabetes mellitus (DM) is a common endocrine disorder in dogs, with a strong breed disposition. The disease is associated with significant morbidity and death when left untreated, and tight control of blood glucose levels is crucial in avoiding the harmful effects of long-standing hyperglycemia. Insulin administration, appropriate diet, and treatment of concurrent diseases which interfere […]
02343-A: Recognizing and Removing Lipemic Interferences for Accurate Laboratory Testing
Grant Status: Closed Grant Amount: $9,113 Unity Jeffery, VetMB; Texas A&M University May 1, 2017 – April 30, 2018 Sponsor(s): Breed(s): -All Dogs Research Program Area: Blood Disorders Donate to Support this Research Program Area Project Summary Over thirty percent of Miniature Schnauzers have primary hyperlipidemia, a disease in which fats (also termed lipids) are […]