02524-E: 2019 Clinician-Scientist Fellowship – University of Pennsylvania
Year 2: Sponsored by the Foundation of the Cairn Terrier Club of America ‘Fellow: Dr. Mariah Gentry Mentor: Dr. Margret Casal
0001943: Congenital Portosystemic Shunts and Hepatorportal Microvascular Dysplasia in Cairn Terriers and Yorkshire Terriers: Clinical Characterization and DNA Linkage Studies
A congenital portosystemic shunt (PSS) is an abnormal blood vessel that allows portal blood to bypass the liver. When blood is diverted around the liver, toxins from the intestinal tract are not filtered by the liver and reach high concentrations in the systemic circulation resulting in clinical signs, such as abnormal behavior and stunted growth. […]
01137: Eradication of Cairn Terrier Ocular Melanosis
Grant Status: Closed Grant Amount: $73,681 Simon M. Petersen-Jones, DVM, PhD; Michigan State University January 1, 2009 – December 31, 2011 Sponsor(s): Bernese Mountain Dog Club of America, Flat-Coated Retriever Foundation, Golden Retriever Foundation, Hoosier Roos Berner Fund Breed(s): Cairn Terrier Research Program Area: Ophthalmology Donate to Support this Research Program Area Project Summary The […]
01413: Investigation into the Genetics of Scottie Cramp: a Genome-Wide Association Study
Grant Status: Closed Grant Amount: $45,320.62 Natasha J Olby, VetMB PhD; North Carolina State University January 1, 2011 – March 31, 2012 Sponsor(s): Airedale Terrier Club of America, American Belgian Tervuren Club, Inc., English Springer Spaniel Field Trial Association, Flat-Coated Retriever Foundation, German Shorthaired Pointer Club of America, German Wirehaired Pointer Club of America, Golden […]
00600: Linkage Analysis of Craniomandibular Osteopathy (CMO) in Terrier Breeds
Craniomandibular osteopathy (CMO) is a painful bone disease that affects the quality of life of both the affected animals and their owners. It is most prevalent in the Cairn Terrier, West Highland White Terrier, and Scottish Terrier breeds. Although it is possible to identify carriers of the disease gene by test breeding, this method has […]
0001614: Development of a DNA-Based Diagnostic Test for Craniomandibular Osteopathy of the Cairn Terrier, West Highland White Terrier, and Scottish Terrier Breeds
Grant Status: Closed Grant Amount: $60,000 Patrick Venta, PhD; Michigan State University September 25, 1998 – September 24, 2000 Sponsor(s): Scottish Terrier Club of America, The Foundation of the Cairn Terrier Club of America, Westie Foundation of America, Inc. Breed(s): West Highland White Terrier, Cairn Terrier, Scottish Terrier Research Program Area: Musculoskeletal Conditions and Disease […]
03094-MOU: Identification of Gene Mutation Underlying Ocular Melanosis in Cairn Terriers
Ocular Melanosis (OM) is an important cause of vision loss and pain in the Cairn Terrier breed. It is an inherited condition and there is a need for a genetic test to allow dog breeders the opportunity to eradicate the condition. The condition develops in both eyes and results from a proliferation of pigmented cells […]
00903-A: Candidate Gene Investigation of Cairn Terrier Ocular Melanosis
Ocular melanosis is an intractable, blinding and painful genetic disease that primarily affects Cairn Terriers. The affected dogs have a slowly progressive accumulation of pigmented cells within the eye that eventually impedes drainage of the intraocular fluid, called aqueous humor, from the eye into the blood stream. This results in an increased pressure within the […]
01592: Investigation into the Genetics of Scottie Cramp: Sequencing of Associated Chromosomal Regions
Scottie Cramp is an episodic disorder of Scottish Terriers that produces a dramatic increase in muscle tone with excitement or exercise. The cause of the disease is unknown, although pharmacologic studies suggest that abnormal signaling between neurons plays a role. The disease is hereditary and is transmitted by an autosomal recessive trait. As a result, […]
02475-A: Effect of Periodontal Treatment on Glycemic Control in Canine Diabetic Patients: A Prospective, Clinical Study
Diabetes mellitus (DM) is a common endocrine disorder in dogs, with a strong breed disposition. The disease is associated with significant morbidity and death when left untreated, and tight control of blood glucose levels is crucial in avoiding the harmful effects of long-standing hyperglycemia. Insulin administration, appropriate diet, and treatment of concurrent diseases which interfere […]