2022 Awarded Grants
Our new grants for 2022 are listed below. Please see our Research Grants Portfolio for a full list of our active grants.
To support one of these grants, or any of the research program areas, please visit our website or use our donation form. If you would like to discuss research support opportunities, please email chfgrants@akcchf.org.
Grant
|
Title |
Research Program
|
The Effect of Overweight and Obesity on Adult Stem Cell Function for Regenerative Therapies in Dogs |
Musculoskeletal Conditions and Disease |
Can Deep Learning (CNN) Detect Minimal Residual Disease (MRD) in Dogs Treated for Lymphoma? |
Oncology - Lymphoma |
The Use of Artificial Intelligence and Computed Tomography Image Features to Predict Sentinel Lymph Node Metastasis in Dogs with Oral Tumours |
Oncology |
Optimizing GBLUP and Machine Learning Genomic Breeding Values for Health and Performance Traits in Working Dogs |
General Canine Health |
Comparison of Sedated Respiratory-Gated Computed Tomography (CT) to Anesthetized Inspiratory:Expiratory Breath Hold CT in Dogs |
Lung and Respiratory Disease |
Investigation into the Prevalence and Clinical Significance of Vector-borne Pathogen Coinfections in a Population of Trypanosoma cruzi-infected Dogs from Texas |
Immunology and Infectious Disease |
Identification of Gene Mutation Underlying Ocular Melanosis in Cairn Terriers |
Ophthalmology |
Cooling Strategies During Exertional Hyperthermia |
General Canine Health |
AGILE (AGility Innovations Leveraging Electronics) - An Initial Study of Technology for Quantifying Canine Agility-specific Activity |
Musculoskeletal Conditions and Disease |
Evaluating Reproductive Diseases in vitro with a 3D Canine Endometrial Organoid Model |
Reproductive Conditions |
Sentinel Lymph Node Mapping for Dogs with Lung Tumors |
Oncology |
Thoracoscopic-Guided Autologous Blood Injection for Treatment of Primary Spontaneous Pneumothorax |
Lung and Respiratory Disease |
Prognostic Biomarkers for the Development of Drug Resistance in Dogs with Idiopathic Epilepsy |
Epilepsy Initiative |
Antimicrobial Resistance in the Canine Vaginal Microbiome |
Reproductive Conditions |
Artificial Intelligence and Machine Learning for Diagnosis of Dog Sperm Morphology |
Reproductive Conditions |
Identification of Novel Epilepsy Genes in Dogs |
Epilepsy Initiative |
Mapping Microstructural Myelin and Axonal Damage in Dogs with Idiopathic Epilepsy using Diffusion MRI and Tract-Based Spatial Statistics |
Epilepsy Initiative |
Novel Biomarker and Therapeutic Target for Chronic Kidney Disease in Dogs |
Kidney & Urological Disease |
Evaluation of the Efficacy of Antioxidant Treatment on Active Kidney Damage and Oxidative Stress |
Kidney & Urological Disease |
Tolerability and Clinical Efficacy of Acetazolamide for Treatment of Hypochloremia in Canine Congestive Heart Failure |
Cardiology |
Judicious Antibiotic Use in Cases of Canine Pyelonephritis |
Kidney & Urological Disease |
Early Detection of Canine Osteosarcoma |
Oncology - Osteosarcoma |
Catechol O-Methyltransferase as a Molecular Drug Target in Heartworm |
Cardiology, Immunology and Infectious Disease |
Evaluating Magnetic Resonance Imaging for Quantifying Histotripsy Ablation in Canine Osteosarcoma |
Oncology - Osteosarcoma |
Molecular Characterization of Canine Soft Tissue Sarcomas Using Spatially Defined Proteomics and Transcriptomics |
Oncology |
A GD3 Nano-scaled Liposomal Cancer Vaccine Clinical Trial for Canine Hemangiosarcoma |
Oncology - Hemangiosarcoma |
The Immune and Molecular Landscape of Canine Osteosarcoma at the Single-Cell Level |
Oncology - Osteosarcoma |
Whole-Exome and Transcriptome Sequencing of Canine Small Cell B Cell Lymphoma and Comparative Analysis to Diffuse Large B Cell Lymphoma |
Oncology - Lymphoma |
Characterizing the Immunomodulatory Response of Histotripsy in Canine Osteosarcoma |
Oncology - Osteosarcoma |
Suppression of Extracellular Glutamate Efflux & mGluR1 Signaling to Impede Canine Hemangiosarcoma Cell Growth |
Oncology - Hemangiosarcoma |
Evaluation of a Targeted Anti αvβ3 Integrin Near-InfraRed (NIR-) Dye for Controlled Resection of Naturally Occurring Soft Tissue Sarcomas in Dogs |
Oncology - Osteosarcoma, Oncology |
Evaluating Accuracy for Identification of Sentinel Lymph Nodes in Dogs with Cutaneous MCT: A Comparison |
Oncology |
Chimeric BiTE-redirected Anti-viral T Cells for Fratricide of Minimal Residual Disease in T-cell Malignancies |
Oncology - Lymphoma |
Investigating Extracellular Crosstalk Between Canine Osteosarcoma and Macrophages |
Oncology - Osteosarcoma |
Genome-wide Identification and Characterization of Peptide Epitopes from Ehrlichia canis and Anaplasma platys with Potential to be Used as Vaccine Candidates |
Tick-Borne Disease Initiative |
Evaluation of Serum C-reactive Protein as a Noninvasive Biomarker of Inflammation and Disease Severity in Dogs with Gallbladder Mucocele |
Hepatic Disease |
Characterizing Immunohistopathology and Serum Immunoglobulin G in Immune-Mediated Chronic Hepatitis Dogs |
Hepatic Disease |
Corneal Cross-linking as Treatment for Corneal Ulceration - “Using Light to Save Sight” |
Ophthalmology |
Canine Systemic Insecticides as a Novel Intervention to Protect Dogs from Triatomine Insect Vectors of Chagas Disease |
Immunology and Infectious Disease |
It’s All In The Genes: The Mutational Landscape of Acute Myeloid Leukemia in Dogs |
Blood Disorders, Oncology |
Plasminogen-activator Inhibitor-1 (PAI-1) and Impaired Fibrinolysis in Immune-Mediated Hemolytic Anemia |
Blood Disorders |
Enhanced Detection and Characterization of Spotted Fever Group Rickettsia Species in Dogs and Ticks with Focus on a Novel Rickettsia Species Infecting Clinically Ill Dogs in the U.S. |
Tick-Borne Disease Initiative , Immunology and Infectious Disease |
The AKC Canine Health Foundation funds research in 23 different Research Program Areas for the health of all dogs. These program areas enable the Foundation to create depth in our research portfolio and help us to be responsive to the health concerns of our constituents.
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.