2021 Awarded Grants


Our new grants for 2021 are listed below.  Please see our Research Grants Portfolio for a full list of our active grants.
To support one of these grants, or any of the research program areas, please visit our website or use our donation form. If you would like to discuss research support opportunities, please email chfgrants@akcchf.org.

Grant

 Title

 Research Program

 02952

Genetics of X-linked Progressive Retinal Atrophy in Greyhounds

Ophthalmology

 02946

Towards Curative Outcomes in Canine Hemangiosarcoma

Oncology - Hemangiosarcoma

 02978-A

Babesia Species in Thrombocytopenic Dogs in the Upper Midwest, USA

Tick-Borne Disease Initiative

 02963

Genetics of Glaucoma in the Entlebucher Mountain Dog

Ophthalmology

 02959

Genetic Basis of non-HSF4 Hereditary Cataracts in a Family of Miniature American Shepherds

Ophthalmology

 02955

Towards Precision Medicine for Canine Cardiac Disease: A Genomic and Machine-Learning Approach to Prediction of Risk and Outcomes in Canine Myxomatous Mitral Valve Disease

Cardiology

 02942

Genome-wide Molecular Interrogation of Canine Hemangiosarcoma

Oncology - Hemangiosarcoma

 02931

Assessment of Frequency of Seizures and Antiseizure Drug (ASD) Efficacy by Electroencephalography (EEG) for Dogs with Epilepsy

Epilepsy Initiative

 02912

Adoptive Natural Killer (NK) Cell Immunotherapy for Canine Lymphoma

Oncology - Lymphoma

 02948-A

Effect of Glycemic Control on the Onset of Cataract Development in Diabetic Dogs

Ophthalmology, Endocrinology

 02950-A

Late-onset Hereditary Cataract in the Boston Terrier: A Whole Genome Sequencing Approach

Ophthalmology

 02851-A

Development of Regional Anesthesia Techniques to Treat Chronic Painful Conditions of the Stifle and Elbow in Dogs

Musculoskeletal Conditions and Disease

 02943-MOU

Identification of Genetic Risk Factors in Degenerative Myelopathy in German Shepherd Dogs

Neurology

 02849-A

Development and Validation of a New Body Condition Scoring System for use in Canine Athletes

Musculoskeletal Conditions and Disease

 02900

Optimizing Storage Conditions of Canine Feces for Fecal Microbiota Transplantation

Gastrointestinal Disease

 02907

Ultrasound-guided Histotripsy Ablation of Canine Brain Tumors through an Acoustically Transparent Cranial Window

Oncology

 02880

Enhanced Surgical Margin Imaging with Polarization-sensitive Optical Coherence Tomography in Canine Soft Tissue Sarcoma and Mammary Tumors

Oncology

 02930

A Dose Finding Study of Cannabidiol in Dogs with Idiopathic Epilepsy

Epilepsy Initiative

 02936

Validating Genetic Variants Underlying Canine Idiopathic Epilepsy and Exploring Their Functional Roles in the Belgian Sheepdog and Tervuren

Epilepsy Initiative

 02940

Investigating Neuronal Network Connectivity in Dogs with Idiopathic Epilepsy using Functional Magnetic Resonance Imaging

Epilepsy Initiative

 02945-MOU

Understanding the Genetic Basis of Addison’s Disease in Portuguese Water Dogs

Endocrinology

 02875

Canine Pituitary Adenoma Organoids (CaPitO) as an in vitro Model for Canine Cushing's Disease

Endocrinology

 02838

Standardization of rLiNTPDase2 and Derived Chimeras as Antigens on Immunochromatographic Assay for Diagnosis of Canine Visceral Leishmaniasis

Immunology and Infectious Disease

 02899

How do Maternal, Environmental, and Genetic Factors Contribute to Acquisition and Evolution of the Enteric Microbiome in Dogs?

Gastrointestinal Disease

 02921-MOU

Transcriptome Profiling of Canine Familial Dermatomyositis Skin Lesions and Treatment with a JAK Inhibitor to Identify Novel Pathways Involved in Pathogenesis

Dermatology and Allergic Disease

 02879

Use of CRISPR-based Genome-wide Approach for Identification of Vulnerabilities in Canine Oral Melanoma

Oncology

 02885

Exposure to Environmental Chemicals in Boxers with Lymphoma

Oncology - Lymphoma

 02858-A

Investigation of Mechanisms of Resistance to Immunotherapy in Dogs with Spontaneous High-grade Glioma

Oncology

 02868-A

Characterization of Mesenchymal Stromal Cell Properties of Canine Culture-expanded Articular Chondrocytes

Musculoskeletal Conditions and Disease

 02920

Continued Investigation into Tumor-permissive Collagen Signatures in Canine Mammary Gland Tumors: Development of Prognostic Markers and Targeted Therapies for Improved Outcomes

Oncology

 02855-A

Repurposing Drugs to Modulate Myeloid-derived Suppressor Cells (MDSCs) in Canine Soft Tissue Sarcomas

Oncology

 02890

Characterizing the LINE-1 Transcriptome in Canine High-grade Peripheral T-cell Lymphoma by RNAseq to Gain Insight into Mechanisms of Drug and Immune Resistance

Oncology - Lymphoma

 02910

Open-Label, Phase-2 Clinical Trial of Chlorambucil and Toceranib for Canine Mast Cell Tumors

Oncology

 02850-A

Potential Reduction of Systemic and Pancreatic Inflammation using Fenofibrate in Diabetic Dogs

Endocrinology

 02864-A

Luteinizing Hormone Receptor Activation in Canine Hemangiosarcoma Cells

Oncology - Hemangiosarcoma

 02859-A

Acute Gastrointestinal Injury in Dogs

Gastrointestinal Disease

 02829

Investigating the Potential of Phage Therapy to Tackle Staphylococcus pseudintermedius Infections in Dogs

Dermatology and Allergic Disease

 02819

Identification of Bartonella henselae In Vivo Induced Antigens for Development of a Reliable Serodiagnostic Assay for Canine Bartonelloses

Tick-Borne Disease Initiative

 02861-A

Cardiovascular Complications of Acute Pancreatitis in Dogs

Gastrointestinal Disease

The AKC Canine Health Foundation funds research in 23 different Research Program Areas for the health of all dogs. These program areas enable the Foundation to create depth in our research portfolio and help us to be responsive to the health concerns of our constituents.

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