03257: B cell Subset Analysis Through Spatial Transcriptomics with Application to B cell Disorders
Grant Status: Open
Abstract
The investigators will compare gene expression changes in these B cell diseases to normal B cell subsets. This work will help to determine which type of B cell is affected in these disease states and which mechanisms are affected. By determining the mechanisms that drive disease, we can identify potential therapeutic targets to improve the treatment of these diseases. The goal of this work is to advance our knowledge of the immune system in dogs and improve the understanding of three canine B cell diseases.
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.