02841: Antigen Discovery for an Improved Serologic Diagnostic of Trypanosoma cruzi Infection in Dogs
Grant Status: Open
One Health: Yes
Abstract
Chagas disease is caused by Trypanosoma cruzi (T.cruzi) parasites and it represents a major public health problem in the Americas. Dogs play a key role in parasite transmission cycles and can develop severe cardiac disease following infection with the parasite. Infection in dogs has been reported in multiple states in the U.S., but the lack of accurate diagnostic tests complicates disease surveillance and reliable identification of cases. There is a critical need for a more reliable test that can detect all infections with this parasite. This study aims to develop a new test for the accurate diagnostic of T. cruzi infection in dogs. The availability of a new diagnostic test may facilitate timely identification of Chagas disease cases and improvine veterinary care. The test may also be broadly applicable to other species and could lead to an improved test for humans.
Publication(s)
None at this time.
Related Grants
- 02632: Canine Chagas Disease: Characterizing Cardiac Disease and Developing Screening Recommendations for Asymptomatic Dogs Seropositive for Trypanosoma cruzi
- 02448: Canine Chagas Disease: Characterizing Cardiac Abnormalities, Vector Infection and Control Strategies, and Parasite Strains in Kennel Environments
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.
