01872-A: Using Ultrasound as a Cost Effective and Non-Invasive Technique for Early Diagnosis of Solid Tumors
Grant Status: Closed
Project Summary
This study was being conducted at the Louisiana State University School of Veterinary Medicine. We enrolled 20 dogs in the healthy group and 46 in the affected group to this date that corresponds to 80% of the intended number of affected dogs (60). The healthy dogs ranged in age from 1 to 11 years and in weight from 2.6kg to 55 kg, 10 were female spayed and 10 were male neutered with the majority of dogs being mixed breed (15). The most common breeds included in the affected group were Labrador Retrievers (12), Mixed breed (6), Boxer (5) and 3 Golden Retrievers. Dogs ranged in age from 3 to 14 years and in body weight from 2.6 to 43.2 kg. Images were obtained by a single radiologist (NR) and included evaluation of multiple lymph nodes. Within the affected group a total of 21 mandibular, 18 retropharyngeal, 12 prescapular, 14 medial iliac and 9 popliteal lymph nodes were evaluated. Additional 19 lymph nodes evaluated included: Cervical, colic, inguinal and jejunal lymph nodes. Cases enrolled within the affected group included 12 dogs with carcinoma, 10 with lymphoma, 7 with mast cell tumor, 6 with sarcoma, 5 with melanoma and 3 cases with abscesses. Detailed data and image evaluation as well as statistical analysis is pending as well as manuscript preparation. At this point, we feel that we have collected enough cases to have a thorough and meaningful evaluation that will allow us to draw conclusions on the cases already enrolled. Therefore, we do not think that continuation of the study will be beneficial.
Publication(s)
None at this time.
Related Grants
- 00978-A: Isolation of the Canine Telomerase Reverse Transcriptase (TERT) Subunit and Generation of Dominant-Negative Mutants for Telomerase Inhibition
- 00888-A: Generation of Canine Single Chain Fragment Variable Antibody Libraries for the Identification and Targeting of Tumor-Associated Antigens in the Dog
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.
