Targeting the T helper cell inflammatory pathway in meningoencephalomyelitis of unknown etiology
Meningoencephalomyelitis of unknown etiology (MUE) is a disorder of dogs that results in inflammation of the brain and/or spinal cord causing depression, seizures, blindness, difficulty walking, and death. MUE is common but unfortunately, brain biopsy is the only means of definitive diagnosis prior to death and the ideal treatment is not known. There is a critical need to improve diagnosis and treatmentof MUE. The investigator will identify changes in the immune system associated with the inflammation that occurs in the brains and spinal cords of affected dogs.
Healthy toy breed dog -OR- toy breed dog diagnosed with MUE, GME, or NME
Owner's Responsibilities (Samples and Information to be collected):
Need medical records (including MRI if available) + blood sample to be collected in coordination with your veterinarian
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.