Identification of Genetic Markers for Subvalvular Aortic Stenosis in Rottweilers

Breed(s): Rottweiler
Sample Type: DNA Sample
Study Location: University of California, Davis
CHF-funded Grant: 02520-MOU

Subvalvular aortic stenosis (SAS) is one of the most common diagnosed heart defects in dogs and the Rottweiler breed has a high prevalence for SAS. Mildly affected dogs may have a normal lifespan, but moderate or severely affected dogs are at risk for developing cardiac complications. There are currently no surgical or pharmacological intervention available that can significantly increase the lifespan of affected Rottweilers. The aim of this study is to identify genes/variants associated with SAS in Rottweiler that can be used to develop a genetic test for this condition

Owner's Responsibilities (Samples and Information to be collected):

1.    Submission of 2-3ml of whole blood in a purple top EDTA tube.
2.    A copy of the 3-generation pedigree (if available)
3.    A copy of the echocardiogram report from a board certified cardiologist
4.    Completed enrollment form

To receive a copy of the enrollment form and if you have questions regarding sample submission or the study please email 

Breed(s) Included:


Read more about this study!


Contact Information:

Participation Contact Information:

Name: Eric Ontiveros
Phone: 530-752-4892

Help Future Generations of Dogs

Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.

Learn How to Help

Get Canine Health News:
Please leave this field empty
American Kennel Club Canine Health Foundation, Inc

8051 Arco Corporate Dr.
Suite 300
Raleigh, NC 27617

Tax ID# 13-3813813

   2020 GuideStar logo

© 2021 AKC Canine Health Foundation | Privacy Policy | Site Map

Site by Blackbaud, Inc.