Identification of Genetic Markers for Subvalvular Aortic Stenosis in Rottweilers
Subvalvular aortic stenosis (SAS) is one of the most common diagnosed heart defects in dogs and the Rottweiler breed has a high prevalence for SAS. Mildly affected dogs may have a normal lifespan, but moderate or severely affected dogs are at risk for developing cardiac complications. There are currently no surgical or pharmacological intervention available that can significantly increase the lifespan of affected Rottweilers. The aim of this study is to identify genes/variants associated with SAS in Rottweiler that can be used to develop a genetic test for this condition
Owner's Responsibilities (Samples and Information to be collected):
1. Submission of 2-3ml of whole blood in a purple top EDTA tube.
2. A copy of the 3-generation pedigree (if available)
3. A copy of the echocardiogram report from a board certified cardiologist
4. Completed enrollment form
To receive a copy of the enrollment form and if you have questions regarding sample submission or the study please email firstname.lastname@example.org.
Participation Contact Information:
Name: Eric Ontiveros
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.