Characterization of Renal Disease in American Boxer Dogs

Breed(s): Boxer
Sample Type: DNA Sample, Tissue Sample
Study Location: The Ohio State University
CHF-funded Grant: 02437-MOU

Kidney disease is a significant problem in dogs. Boxers appear to be predisposed to developing chronic, progressive renal disease, and there might be a genetic basis in this breed. Examination of blood samples, urine and kidney tissue from affected Boxers is needed to identify potential genetic mutations that could be responsible for the disease.

This study is being performed by the International Veterinary Renal Pathology Service (IVRPS), which is a collaborative effort between the Ohio State University and Texas A&M University through a grant from the American Kennel Club-Canine Health Foundation. The Primary Investigators are Dr. Jessica Hokamp and Dr. Rachel Cianciolo. This study is supported by the American Boxer Charitable Foundation.

If you participate in this study, a veterinarian or veterinary technician will collect urine and a small blood sample from your dog to measure amounts of certain molecules. This blood sample will also be used to harvest DNA from the cells in the event that genetic testing is warranted. In certain instances, your veterinarian might recommend performing a kidney biopsy. This is a diagnostic tool used to determine the cause of the kidney disease. If you choose to have your dog undergo the biopsy, your dog will be anesthetized and a small portion of kidney tissue will be harvested.

The urine, blood samples, and tissue from kidney biopsy will be submitted to the IVRPS, where evaluation of the samples will be performed at no charge and the diagnosis can help guide treatment. Please note that the even though the evaluation of the samples will be free, your veterinarian will charge for the  biopsy/sample collection procedures.

Read more about this study!

More Information


Contact Information:

Name: Dr. Jessica Hokamp
Phone: 614-688-3159

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