Diagnostic Criteria for Golden Retriever Pigmentary Uveitis
CHF Grant 02569-MOU: Development of a Polygenic Risk Model for Pigmentary Uveitis in Golden Retrievers
Publication: Townsend, WM, Huey, JA, McCool, E, King, A, Diehl, KA. Golden retriever pigmentary uveitis: Challenges of diagnosis and treatment. Vet Ophthalmol. 2020; 00: 1– 11. https://doi.org/10.1111/vop.12796
What can we learn?
Golden Retriever Pigmentary Uveitis (GRPU) is an inflammatory eye disease with severe, vision-threatening complications seen in Golden Retrievers, but with an unknown mode of inheritance. This publication presents a consensus statement from the American College of Veterinary Ophthalmologists’ Genetics Committee regarding the diagnostic criteria for GRPU.
Uveal cysts do not have to be visualized in order to make a diagnosis of GRPU.
Hypotony does not have to be present for a diagnosis of GRPU.
“If radial pigment is present on the anterior lens capsule, the eye should be marked as affected by GRPU even if aqueous flare, free floating pigmented cells, hypotony, and/or conjunctival hyperemia are not present.”
Conclusion: All dogs with radial pigment on the anterior lens capsule should be diagnosed as affected with GRPU. Any Golden Retriever presenting with non-specific ocular symptoms or those associated with uveitis should be referred to a specialist for definitive diagnosis since early recognition and treatment of GRPU offers the best chance for a positive outcome.
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