Oncology Grants

In continuation of CHF’s strong support of canine cancer research, the Oncology Research Program Area remains committed to innovative research that will aid in the discovery of advanced diagnostic technology and therapeutic target identification.

To make sense of the complexity of cancer, new approaches are needed to provide comprehensive characterization of tumors and other canine cancers. These approaches will likely require broad bioinformatic analyses, high throughput methodologies and systems biology tools.

Active Grants:

Previously Awarded Grants:

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 02071 Development of a Therapeutic Brain Tumor Vaccine
 02093-A Sequencing Histiocytic Sarcoma (HS) loci identified by Genetic Association studies in the Bernese Mountain Dog (BMD)
 02091-A Differentiating between Localized and Disseminated Histiocytic Sarcoma in Bernese Mountain Dogs
 01822 Beyond the Genome: The Intersection of Genes and the Environment in Canine Cancer
 01843 Further Investigation of the Genes Controlling Canine Leukemia to Properly Diagnose and Control the Disease
 01872-A Using Ultrasound as a Cost Effective and Non-Invasive Technique for Early Diagnosis of Solid Tumors
 01426 Personalized Medicine for the Treatment of Canine Mast Cell Tumors
 01577 Identifying the Genes Conferring Risk for Transitional Cell Carcinoma
 1633 Novel Therapy for Melanoma, Lymphoma, Meningioma and Nephroblastoma
 01557 Narrowing the Search for the Genetic Basis of Histiocytic Malignancies
 01914-A Defining the Genes That Contribute to the Development of Soft Tissue Sarcomas
 01669-A Determining the Role of Bacterial Infection in Complications after Chemotherapy
 01861-A Preventing Heart Damage during Chemotherapy through Early Detection of Cardiotoxicity
 01683-A Improving Resection of Tumors through Enhanced Imaging
 01686-A Identifying Drugs That Will Kill Cancer Stem Cells
 01912-A Enhancing the Safety and Efficacy of Anti-Cancer Drugs in Dogs
 01929-A Arginine Dependence: Identification of Cancer's Achilles Heel
 01703-A Enhancing Natural Anti-Tumor Immune Responses during Chemotherapy
 01472 Enhanced Killing of Malignant Histiocytosis with a Novel Combination of Anti-Tumor Drugs
 01876-A Ensuring That Emerging Stem Cell Treatments Do Not Activate or Exacerbate Cancer in Dogs
 01692-A Accurate Diagnosis of Mast Cell Tumor Metastasis
 01422 Targeting iNOS in Canine Oral Melanoma
 1093B-T Positional Cloning of the Gene(s) for Gastric Cancer in the Chow Chow
 790 MicroRNA Profiling and MicroRNA-Based Treatment of Canine Cancers
 01708-A Validation of a general method for enrichment of canine cancer stem cells

The AKC Canine Health Foundation funds research in 23 different Research Program Areas for the health of all dogs. These program areas enable the Foundation to create depth in our research portfolio and help us to be responsive to the health concerns of our constituents.

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