Immunology and Infectious Disease Grants
The Immunology Research Program Area is combined with the Infectious Disease Research Program Area because there is substantial overlap in protection against and resolution of pathogenic infection and immunity against pathogens. This research seeks to define unique and evolutionarily conserved features of canine immune response pathways and determine how these pathways initiate, sustain, moderate, and resolve immune responses in dogs.
Active Grants:
| 02633 | Validation and Diagnostic Performance of a Novel Monoclonal Antibody based Histoplasma Urine Immunoassay in Dogs with Histoplasmosis |
| 02647-A | Investigation of Cytokine Biomarkers for the Diagnosis of Canine Tuberculosis |
| 02532-A | Canine Influenza: Occurrence, Spatial and Temporal Trends and Identifying Modifiable Factors to Reduce Transmission at Events in the United States |
| 02407-A | In vitro Efficacy of Nano-sulfur Against Planktonic and Biofilm State of Resistant Bacteria |
| 02408 | Predicting the Outcome of Coccidioidomycosis in Naturally Infected Dogs |
| 02441 | Evaluation of a New Vaccine for Canine Brucellosis |
| 02458-A | A Laboratory Test for Detecting Drug Resistance in Canine Heartworm Disease |
| 02448 | Canine Chagas Disease: Characterizing Cardiac Abnormalities, Vector Infection and Control Strategies, and Parasite Strains in Kennel Environments |
| 02404-A | The Impact of Lidocaine Administration on Natural Killer Cell Populations in Canine Sepsis |
| 02380-A | Estimating Prevalence and Identifying Risk Factors for Canine Leptospirosis in North America |
Previously Awarded Grants:
| 02461-A | Innate immune response to Leptospira in naturally exposed dogs |
| 02245-MOU | Genetic Predisposition to Avian Tuberculosis in Miniature Schnauzers and Bassets Hounds |
| 01699-A | Preventing Inaccurate Diagnosis of Brucellosis |
| 02299-A | Investigating Recovery of the Skin Microbiota after Surgery |
| 1771 | Defining the Unique Genetic Markers in Dogs That Define Immune Function, Disease Resistance and Tissue Transplantation |
| 1988 | Identification of a Safe Storage Time for Canine Blood Used In the Treatment of Anemia |
| 2002 | Defining the Genetic Basis of Inflammatory Bowel Disease |
| 02180-A | Exploring the Canine Immune System for New Treatments |
| 02128-A | Redefining the Recommendations for Prevention of Infectious Disease at Dog Shows and Other Areas Where Dogs Meet and Compete |
| 02050 | Defining the Genetic Susceptibility to Granulomatous Colitis, a Severe Form of Inflammatory Bowel Disease |
| 02187-MOU | Investigating Symmetrical Lupoid Onychodystrophy in Bearded Collies |
| 02052 | Defining the Mechanism of Severe, Life-Threatening Bleeding Disorders in Dogs |
| 02102-A | Stopping Tick Infestation to Prevent Human and Canine Disease |
| 2083-A | Stemming the Growing Epidemic of Drug Resistant Bacteria |
| 01857-A | Decreasing the Mortality Rate of Shock through Enhanced Monitoring of Tissue Oxygen Levels |
| 01895-A | Using a Novel Diagnostic Test to Guide the Treatment of a Common Fungal Pathogen Encountered by Field Trial and Hunting Dogs |
| 01894-A | Documentation of Disease-Causing Ticks in a Field Trial Environment for the Purpose of Developing Practical and Cost-Effective Strategies for Tick Control |
| 01900-A | Prevalence of Vector Borne Disease in Dogs with Clinical Signs of Immune Mediated Disease |
| 01480 | Leptospirosis: An Emerging Health Concern for Field Trial and Hunting Dogs |
| 01860-A | Rapid and Accurate Diagnosis of Bacterial Peritonitis |
| 01701-A | Determining the Effect of Pain Medication on Immune Function: Part 1 |
| 01505-A | Identification of Biological Marker of Idiopathic Immune-Mediated Polyarthropathy to Enable Non-Invasive Diagnosis and Prognosis |
| 01712-A | Determining the Effect of Pain Medication on Immune Function: Part 2 |
| 01265 | Understanding Mechanisms Involved in Canine Autoimmune and Inflammatory Disorders |
| 01521-A | Assessment of grass awn disease in dogs & CRP plantings of grasses with barbed awns |
The AKC Canine Health Foundation funds research in 23 different Research Program Areas for the health of all dogs. These program areas enable the Foundation to create depth in our research portfolio and help us to be responsive to the health concerns of our constituents.
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.
