Samples Needed from Brussels Griffon Dogs

Breed(s): Brussels Griffon
Study Type: Clinical Study
Study Location: University of Georgia

Syringomyelia (SM) has emerged as a common spinal cord abnormality in small breed dogs. Syringomyelia, characterized by the development of excess fluid in the spinal cord, is associated with a syndrome of severe pain and weakness. Certain breeds are predisposed to SM, most notably the Cavalier King Charles Spaniel (CKCS). SM is associated with a condition referred to as a Chiari-like malformation (CM), which is a developmental abnormality of the skull. As a result of the skull malformation, part of the cerebellum and the brainstem may be compressed leading to an alteration in the normal flow of cerebrospinal fluid (CSF) and mild inflammation in the central nervous system. It is hypothesized that these abnormalities contribute to the development of SM.

Recently, SM has been diagnosed in Brussels Griffon (Griffon Bruxellois) dogs in North America, Europe and Australia. Drs. Marc Kent and Simon Platt of the University of Georgia are in the process of studying SM in the Brussels Griffon. Their hypothesis is that a subpopulation of the Brussels Griffon (BG) dog breed is affected by SM. The goals of their research are to identify the prevalence of SM in BG; to delineate clinical signs and spinal fluid abnormalities in BG with SM; and to utilize MRI to define structural abnormalities associated with SM in the BG breed.

Drs. Kent and Platt need your help to increase the number of Brussels Griffons participating in this study. To learn more about how this project, please visit the website of the Veterinary Teaching Hospital at the University of Georgia. At this site, owners can find valuable information regarding the disease process involved in SM, the importance of the study, and enrollment criteria. Applications can be downloaded from the website.

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