Landmark Clinical Trial to Establish the Evidence-Based Use of Regenerative Medicine to Treat Tendon Injury in Dogs

Breed(s): -All Dogs
Study Type: Clinical Study
Study Location: Veterinary Orthopedic and Sports Medicine (VOSM) Group in Annapolis Junction, MD

Supraspinatus tendon injury of the shoulder is common in both companion dogs and canine athletes. It often progresses undiagnosed and results in reduced function, lameness and pain. Failed healing and recurrence frequently occur because unassisted tendon healing results in scar formation.

Regenerative therapies aim to accelerate and promote healing through tissue regeneration rather than scarring. There are several types of cells that promote healing, including platelets from blood, and stem cells from adipose (fatty) tissue taken from the patient’s own body. In this study, platelet rich plasma (PRP) will be combined with one of two types of cell therapy: concentrated adipose stem cells (ASC) and a mixture of adipose-derived cells called the stromal vascular fraction (SVF). Please note that this clinical trial is blinded and placebo-controlled.

Demonstrating an effective treatment for supraspinatus tendon injury will have profound impact on the treatment of musculoskeletal conditions, as well as other types of injuries affecting dogs.

Dogs with primary unilateral supraspinatus tendinopathy and lameness in only the affected limb will be included in the study.

Principal Investigator(s):

Sherman O. Canapp, Jr., DVM, MS, CCRT, DACVS, DACVSMR (Veterinary Orthopedic & Sports Medicine Group)

Jennifer G. Barrett, PhD, DVM, DACVS, DACVSMR (Virginia Tech Equine Medical Center)

This clinical trial is part of CHF Grant 2107.

More Information


Contact Information:
Name: Jayme Pfisterer, Surgical Coordinator, Veterinary Orthopedic & Sports Medicine Group
Phone: 240-295-4400 Ext. 210
Name: Katie Cox, Research Technician, Veterinary Orthopedic & Sports Medicine Group
Phone: 240-295-4400 Ext. 215

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