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The AKC Canine Health Foundation (CHF) is proud to announce approval of 17 research grants to 13 research institutions and universities. These grants, totaling more than $1.7 million in funding for researchers studying canine health, will provide better treatments, more accurate diagnosis, and a deeper understanding of the mechanisms that cause disease.
The projects are categorized into research program areas that allow for support of research broadly through funding of program areas rather than single grants. For example, through our Musculoskeletal Research Program we are approaching Cranial Cruciate Ligament Disease from multiple angles, providing new options for treatment (stem cell therapy and Platelet Rich Plasma therapy) as well as novel evaluation systems (conformation scores and 3D computer evaluation of knee biomechanics) to prevent the disease. We are taking this approach across our major research program areas so that oncology, cardiology and all others can grow and flourish. Please donate today or sponsor a program area.

To detail the goals and significance of the new research projects, we have released a webinar with Dr. Shila Nordone, CHF’s Chief Scientific Officer. Intended for an audience of non-scientists, Dr. Nordone explains how these grants will move canine health forward, eventually helping dogs that come into the veterinary clinic.

Click the grant number for more information. You may also download a printable list of the 2013 grants with project descriptions.
Cardiology
Grant 1753: Identification of genetic factors that alter the severity of cardiomyopathy
Dr. Kathryn M. Meurs, DVM, PhD; North Carolina State University
Grant 1760: Use of gene therapy to treat dilated cardiomyopathy
Dr. Margaret M Sleeper, VMD; University of Pennsylvania
Musculoskeletal Conditions and Disease
Grant 1762: Use of plasma-derived growth factors to heal cruciate rupture
Dr. Peter Muir, BVSc, PhD; University of Wisconsin, Madison
Grant 1782: Defining the elements of successful cranial cruciate ligament repair
Dr. Gina Bertocci, PhD; University of Louisville
Neurology
Grant 1731: A novel approach to understanding how menigoencephalomyelitis develops in dogs
Dr. Nick Jeffery, BVSc; Iowa State University
Oncology
Grant 1843: Investigation of the genes controlling canine leukemia to properly diagnose and control the disease
Dr. Matthew Breen, PhD; North Carolina State University
Grant 1822: Beyond the genome: the intersection of genes and the environment in canine cancer
Dr. Robert K. Wayne, PhD; University of California, Los Angeles
Grant 1826: A novel treatment for brain tumors using a One Medicine approach
Dr. Simon R. Platt, BVMS; University of Georgia / Emory School of Medicine
Grant 1759: Disrupting the differentiation of cancer stem cells to prevent the spread of hemangiosarcoma
Dr. Jaime F. Modiano, VMD, PhD; University of Minnesota
Grant 1787: Clinical advancement of a cancer vaccine in dogs
Dr. Nicola Mason, BVetMD, PhD; University of Pennsylvania
Grant 1806: A novel virus-based anti-tumor treatment for canine osteosarcoma
Dr. Bruce R. Smith, VMD, PhD; Auburn University
Renal Disease
Grant 1766: Identification and validation of the genes that define abnormal development of the kidney in dogs
Dr. Kerstin Lindblad-Toh, PhD; Broad Institute
Grant 1844: Treatment of urinary incontinence with multipotent muscle cells: a regenerative medicine approach to a common canine health problem
Dr. Shelly Vaden, DVM, PhD; North Carolina State University
General Canine Health
Grant 1827: Defining the specific species of bacteria that contribute to canine periodontal disease
Dr. Marcello Pasquale Riggio, PhD; University of Glasgow
Immunology and Infectious Disease
Grant 1771: Defining the unique genetic markers in dogs that define immune function, disease resistance and tissue transplantation
Dr. Aravind Ramakrishman, MD; Fred Hutchinson Cancer Research Center
Grant 1780: Defining the mechanism by which ticks locate dogs in order to better prevent disease transmission
Dr. Emma Natalie Ivy Weeks, PhD; University of Florida
All Program Areas
Grant 1849: Filling the gaps in the canine genome
Dr. Shaying Zhao, PhD; University of Georgia