01857-A: Decreasing the Mortality Rate of Shock through Enhanced Monitoring of Tissue Oxygen Levels
Grant Status: Open
Grant Amount: $12,960
Dr. Kelly Hall, D.V.M., University of Minnesota
July 1, 2012 - June 30, 2013
Breed(s): -All Dogs
Research Program Area: Immunology and Infectious Disease
Abstract Without medical intervention, dogs that develop shock from hemorrhage (e.g., trauma, hemangiosarcoma, gastrointestinal ulcers, etc.), severe dehydration or severe infection are at risk for organ failure and death. The ability to identify shock in veterinary patients is hampered by the diagnostic tests that are available to veterinarians. Standard monitoring (including blood pressure, heart rate, respiratory rate and pulse oximetry) provides insight into an animal's health status but is not specific for shock and has limited ability to guide patient treatment. More invasive methods for identifying and treating critical patients that are used in human medicine are often not financially feasible in the veterinary setting and require advanced training for placement and monitoring. A search for a more sensitive, non-invasive, readily available, and easy to use monitoring tool, is needed to better evaluate veterinary patients, guide therapy more appropriately and improve overall survival. The InSpectra Tissue Spectrometer which monitors tissue oxygenation is an emerging technology that may more effectively help veterinary clinicians identify patients with underlying shock and aid in directing therapy to resuscitate such patients. The objective of this study is to evaluate the use of the InSpectra Tissue Spectrometer as part of a goal directed therapy protocol. The pilot data obtained will be used to design further studies in dogs in an effort to improve outcome in dogs presenting to the emergency room in shock.