DONATE
We need your support to fund research that helps dogs live longer, healthier lives.
Donate Today
00329-A: Genetics of Post-Squalene Cholesterol Biosynthesis in the Havanese, Akita and Samoyed: Are Defects in this Pathway Responsible for an Array of Developmental Abnormalities- A Pilot Study
Grant Status: Closed
Grant Amount: $12,960
Dr. Keith E. Murphy, PhD, Texas A&M University
July 1, 2004 - June 30, 2005
Breed(s): Akita, Havanese, Samoyed
Abstract
This project is designed to eventually identify the causative gene(s) for post-squalene cholesterol biosynthesis. Research focused on cholesterol biosynthesis is increasingly directed towards understanding the genetics governing diseases related to this important sterol. Whereas most metabolic diseases are characterized largely by postnatal biochemical toxicities or deficiencies, disorders of cholesterol biosynthesis are notable for their severe effects on prenatal development.
Support Research
You can make contributions to support the specific areas of research that match your interests or greatest health concern.
Participation Needed
Your help is needed with canine health research. DNA and tissue samples are needed from healthy dogs and dogs affected by certain diseases.
