Renal Disease Research Program RFP
The AKC Canine Health Foundation supports basic science discovery and clinical research into the treatment of renal and urologic disorders through the Renal Disease Research Program. This program supports research into the pathophysiology of disease, the identification of unique/emerging risk factors for the development of renal disease, genetic/epigenetic/proteomic/
metabolomic factors associated with disease development, predictors (biomarkers) of kidney damage and recovery, and identification of potential therapeutic drugs that reduce the pathology associated with disease. Genome Wide Association Studies will be considered responsive; however, phenotype of disease must be thoroughly established and documented prior to consideration of genetic factors associated with disease. Further, collaborative, multi-disciplinary teams of investigators who can approach discovery research from a multi-‘omics’ perspective will be considered more competitive than a genomic approach working in isolation. Regenerative Medicine research is strongly supported by the Renal Disease Research Program.
Key canine health problems addressed by this research program include, but are not limited to:
- Renal Dysplasia
- Renal Failure
- Protein-Losing Nephropathy
- Juvenile Renal Disease
- Renal Amyloidosis
- Cystic Calculi
- Ectopic Ureter
- Shar-Pei Fever
- Fanconi Syndrome
- Renal Cortical Hypoplasia
Of priority are those studies which define mechanism of disease and identify novel biomarkers for early diagnosis and monitoring of disease progression. In addition, basic science regenerative medicine studies that identify novel, cell-free factors that are restorative of damaged kidneys are of strong interest.
The AKC Canine Health Foundation is not currently accepting grant applications in this research program area.
Please read an open letter to applicants concerning changes to our grant process from previous cycles.
Help Future Generations of Dogs
Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.