Immunology and Infectious Disease Research Program Area

The overarching goal of the Immunology Research Program Area is to define unique and evolutionarily conserved features of canine immune response pathways, and to determine how these pathways initiate, sustain, moderate, and resolve immune responses in dogs. This program area supports basic science and clinical research into the pathophysiology of immune-mediated disease, diagnostics, the molecular and genetic basis of immune-mediated diseases and the identification of potential therapeutic drugs that reduce the pathology associated with immune-mediated disease. Regenerative Medicine research is strongly supported by the Immunology and Infectious Disease research program.

Key canine health problems addressed by this research program area include, but are not limited to:

  • Allergies (skin and food allergy cross-listed under dermatology and gastrointestinal research programs) 
  • Immune-Mediated Hemolytic Anemia 
  • Immune-Mediated Thrombocytopenia 
  • Immune-Mediated Arthropathies 
  • Symmetrical Lupoid Onychodystrophy 
  • Lupus Erythematosus 
  • Lupoid Dermatosis

The Immunology Research Program Area is combined with the Infectious Disease Research Program Area because there is substantial overlap in protection against and resolution of pathogenic infection and immunity against pathogens. That said, infectious disease research is not restricted to immunology or vaccinology and can be pathogen-focused in nature if a translational endpoint is evident. Historically the Foundation has biased towards funding research for infectious diseases found in the U.S.

Key canine health problems addressed by this component of the research program area include, but are not limited to:

  • Coccidioidomycosis (Valley Fever) 
  • Leishmaniasis 
  • Leptospirosis 
  • Dirofilariasis (Heartworm) 
  • Herpesvirus 
  • Influenza 
  • Staphylococcis (MRSA) 
  • Aspergillosis 
  • Bordetella (Kennel Cough) 
  • Brucellosis 
  • Parvovirus 
  • Rabies virus

View recently funded research in the Immunology and Infectious Disease Research Program Area

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