2020 Vector-Borne Disease Request for Proposals

AKC Canine Health Foundation

2020 Vector-Borne Disease Request for Proposals (RFP)

As new vector-borne pathogens continue to be identified and the spread of tick-borne disease (TBD) rises, the AKC Canine Health Foundation continues its commitment to address this emergent issue by funding critical research to diagnose, prevent and treat vector-borne diseases in dogs. Diseases of interest include, but not limited to, heartworm disease, leishmaniasis, ehrlichiosis, anaplasmosis, Rocky Mountain spotted fever, hepatozoonosis, babesiosis, bartonellosis, hemotropic mycoplasmosis, and Lyme disease. The Foundation supports a One Health and multi-disciplinary approach to addressing the health needs of all dogs and their people.

CHF is seeking innovative approaches to vector-borne diseases (VBD), including the study of co-infections.

Proposals may address any of the following areas:

  1. Generation of improved and innovative diagnostics for important vector-borne diseases of dogs
  2. Novel approaches to safe and effective preventives, including interruption of pathogen transmission from vector to host
  3. New treatments, including non-antimicrobial and immunotherapeutic approaches to infection/co-infections, and issues of resistance
  4. Documentation of treatment protocols and measured response for specific vector-borne diseases
  5. Pathophysiology and the role of persistent infection in chronic disease causation; Lyme disease in dogs is of particular interest
  6. Surveillance and epidemiological studies, including those addressing public health, especially for newly-emerging vector-borne diseases, and for at-risk populations of dogs. Epidemiological survey to find out if the use of isoxazolines has an impact on the prevalence of TBD/VBD compared to dogs treated with other ectoparasticide-classes
  7. Of special interest are applications proposing the identification of receptor proteins involved in the host-attraction and attachment of tick species of veterinary importance to dogs, including but not limited to Amblyomma americanum and Rhipicephalus sanguineus. Specifically, the use of “omic” tools to improve basic understanding of chemosensory reception and/or transfer of information from the tarsi to the synganglion is encouraged

The deadline for online applications is Monday, March 30th, 2020 at 11:59 PM Eastern. Both Acorn ($15,000 maximum including 8% maximum indirect costs) and Oak (over $15,000 including 8% maximum indirect costs) grant proposals that can be completed within the budget criteria will be accepted for review.

All work completed under this funding must strictly adhere to the Foundation's Humane Use of Animals Policy.  Funding eligibility details can be found here.

Questions regarding this RFP should be directed to Andrea Fiumefreddo, CHF Director of Programs & Operations.

Please forward this announcement to other researchers seeking funding in this area of research.

Acorn Application
Oak Application
Access Saved Applications

Previously awarded CHF grants and active research in these areas can be found here: Tick-Borne Disease and Immunology and Infectious Disease

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