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CHF/GRF Collaborative Cancer Grant RFP

Purpose

This Request for Proposals (RFP), issued jointly by the Golden Retriever Foundation and the AKC Canine Health Foundation, invites grant applications for investigator-initiated Research Projects in the area of canine Hemangiosarcoma or Lymphoma research. Both parent organizations are collaborating in this funding effort in order to increase the likelihood that we will achieve two critical goals: 1) Identification of genomic, epigenomic, proteomic or transcriptomic markers of disease that will aid in the early identification and/or prevention of canine cancer, and 2) Identification or development of therapeutics that will significantly enhance survival and quality of life for dogs with cancer.

Click here to download a PDF Version of the full Request for Proposals.

Click here to begin application process.

Project Structure

This RFP is soliciting integrated, multi-project research programs involving multiple, independent investigators who will share intellectual and physical resources in order to work towards a unified scientific goal. In order to be considered responsive to this RFP, the grant application must have a well-defined unifying research theme and must include at least three component projects. Each individual project must be a scientifically meritorious research effort on its own, with individual projects clearly interrelated and synergistic so that the ideas, efforts, and outcomes of the program project as a whole will offer a distinct advantage over pursuing the individual projects separately. As such, it is strongly encouraged that the research takes a multi-disciplinary approach.

Specific Research Objectives

This joint initiative between the Golden Retriever Foundation and the AKC Canine Health Foundation reflects our ongoing commitment to identification of the genetic, molecular, and cellular determinants of cancer susceptibility, as well as the identification of novel, effective treatment modalities for canine cancer.

Therefore, this RFP invites coordinated research programs in any of the broad areas of cancer research, including but not limited to studies of cancer biology, cancer treatment, cancer diagnosis, cancer prevention, and cancer control. Basic, translational and clinical studies in any of these research areas will be considered responsive.

Topics of special interest include, but are not limited to:

Identification of proteomic, genomic, epigenomic, and transcriptomic biological markers of hemangiosarcoma or lymphoma for diagnostic and prognostic use in high-risk breeds.
Identification or development of canine-specific reagents for use in passive immune therapy in hemangiosarcoma or lymphoma.
Integration of tumor genotyping/phenotyping with therapeutics for the development of personalized treatment strategies.
Identification of novel pathways of tumor survival and points of therapeutic intervention.

Additional Information for Applicants:

Research Partners

Data Sharing and Intellectual property

Application and Submission Information

Review Process

Timeline of the Collaborative Cancer RFP

May 15, 2012 - RFP is active
August 1, 2012 - Letter of Intent Due
October 8, 2012 - Invitations to submit full proposals will be mailed
February 11, 2013 - Full Proposals due
May 15, 2013 - Funding decisions announced