Regenerative Medicine to Treat Orthopedic Injuries in Dogs

In this 40-minute webinar,“Regenerative Medicine for Canine Orthopedic Concerns,” Dr. Sherman Canapp discusses the recent progress in the use of regenerative medicine to treat orthopedic injuries in dogs and also identifies areas where further research is needed.

Designed for both lay and scientific audiences, Dr. Canapp explains the different types of therapy that fall under the category of regenerative medicine, while presenting the stories of three canine clients whose lives were drastically improved through this exciting and innovative treatment.

Dr. Canapp has graciously agreed to answer questions about this webinar. The answers to selected questions will be posted here shortly. To submit a question click here.

To view this video in full-screen mode, press play to start the video, click "vimeo", then click the four arrows pointing outward.

2013 Funded Grants

In this webinar Dr. Shila Nordone, Chief Scientific Officer of the AKC Canine Health Foundation describes the 17 new research grants funded by the AKC Canine Health Foundation for 2013. She describes how these grants will work together as stepping stones to create a path toward improving the health and well-being of the dogs we love so much. This webinar is intended for a non-scientific audience.

To view this video in full-screen mode, press play to start the video, click "vimeo", then click the four arrows pointing outward.

Support the AKC Canine Health Foundation

Watch this video about the importance of supporting the AKC Canine Health Foundation. Three researchers share the significance of our mission.

Many thanks to the North Carolina State University School of Veterinary Medicine for their assistance with this video.

Comparative Cytogenetics of Cancer. Just How Human Are Our Dogs?

Presentation by Matthew Breen, PhD, CBiol, FSB, North Carolina State University, College of Veterinary Medicine Professor of Genomics at the 2011 National Parent Club Canine Health Conference hosted by the AKC Canine Health Foundation.

What We Know About Familial Heart Disease in the Dog

Presentation by Kathryn M. Meurs, DVM, PhD, Professor and the Associate Dean of Research and Graduate Studies at North Carolina State University College of Veterinary Medicine at the 2011 National Parent Club Canine Health Conference hosted by the AKC Canine Health Foundation.

Advances in Diagnosis and Treatment of Canine IBD

Presentation by Albert Jergens, DVM, MS, PhD Professor of Veterinary Clinical Sciences at Iowa State University at the 2011 National Parent Club Canine Health Conference hosted by the AKC Canine Health Foundation.

Presentation Abstract: Canine inflammatory bowel disease (IBD) denotes a heterogeneous group of idiopathic, chronic, relapsing inflammatory disorders of the gastrointestinal tract that are immunologically-mediated. While their exact etiologies remain unknown, research results suggest that interplay between genetic factors and enteric bacteria are crucial for disease development, owing to abnormal host responses directed against the commensal microbiota. Key clinical signs include vomiting, diarrhea and weight loss, and histopathologic lesions of inflammation may involve the stomach, small intestine, or colon. Recent advances in molecular tools, disease activity indices, and biomarker development now permit objective assessment of IBD severity at diagnosis and in response to various therapies. Treatment of IBD involves both dietary and pharamacologic interventions as well as therapeutic manipulation of the enteric microbiota through the use of antibiotics, prebiotics, and probiotics. This presentation will highlight recent research advances in canine IBD and offer insight into future research directions.

Recent Progress in Molecular Genetics of Cancer and Challenges Ahead

Presenation by Jaime F. Modiano, VMD, PhD, Director, Animal Cancer Care and Research Program, University of Minnesota College of Veterinary Medicine at the 2011 National Parent Club Canine Health Conference hosted by the AKC Canine Health Foundation.

Presentation Abstract: The last decade has seen dramatic improvements in molecular genetic research of canine cancer. This includes new and improved diagnostic tests and approval of the first immune-based cancer therapy (ONCEPT, Merial canine melanoma vaccine) and the first targeted small molecule inhibitor (Palladia, Pfizer c-Kit inhibitor for treatment of mast cell tumors). There also has been significant progress defining breed-associated cancer susceptibility. Our efforts have focused on defining the role that “breed” plays not only on the frequency of tumor occurrence, but also on tumor behavior. At the same time, we have dedicated considerable effort to understand the mechanisms that drive tumor behavior as a means to improve our diagnostic precision, our prognostic capacity, and the development of new therapies. To help achieve these goals, AKC CHF has supported eight research projects in our laboratory since 1998. These projects have allowed us to build a sample bank that has been used extensively by the research community worldwide (more than 40 investigators at more than 30 companies, universities, and research institutes in seven countries and four continents). The projects also have formed a robust foundation for clinical translation, verifying the notion that oftentimes tumors are as unique as patients and we must beware of generalizations and oversimplification. This presentation will underscore the differences that exist within tumors and among dog breeds, and illustrate how we have started to overcome these challenges to achieve our clinical goals.

Dog Genetics and the Mammalian Mind

Presentation by Mark W. Neff, PhD of the Van Andel Research Institute (VARI) at the 2011 National Parent Club Canine Health Conference hosted by the AKC Canine Health Foundation

The History of Veterinary Medicine and Canine Research

Presentation by Donald F. Smith, DVM, Cornell University Professor of Surgery at the 2011 National Parent Club Canine Health Conference hosted by the AKC Canine Health Foundation. Smith maintains a robust DVM student teaching schedule and serves as chair of Cornell’s veterinary admission committee. He lectures nationally on topics ranging from “One Medicine, One Health” to the History of Veterinary Medicine.

Canine Degenerative Myelopathy

Presentation by Joan R. Coates, DVM, MS, University of Missouri Professor of Veterinary Neurology & Neurosurgery at the 2011 National Parent Club Canine Health Conference hosted by the AKC Canine Health Foundation.