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Salmonella is an organism that strikes fear due to its potential to cause severe gastrointestinal illness, but it is not a word many people associate with cancer therapy. Think again. Dr. Dan Saltzman of the University of Minnesota Medical School and his colleagues have taken Salmonella organisms, weakened them using genetic engineering to eliminate their disease-causing potential, and developed a new drug by adding Interleukin-2 (IL-2), a series of proteins that act as “flavors” to activate the immune system.
Historically, the survival time of dogs with meningiomas treated with surgery alone has been four and one-half to seven months. Systemic therapies so far have had limited effectiveness. However, based on preclinical data from our research program,we embarked on the development of anti-tumor vaccinations to treat dogs with spontaneous meningiomas after surgical removal.
Researchers at the University of Minnesota are currently conducting clinical trials to find new and better ways to treat gliomas. In the past 12 months, they have recruited 10 dogs for a gene therapy study. Preliminary data hint at improved times of progression-free as well as overall survival in dogs treated with gene therapy.
Recently Dr. Nancy Kay saw two cases of pneumothorax in her practice. Recognizing the condition is key to dogs recover from this condition most often caused by a trauma.
Researchers more than ever are adhering to the concept of One Medicine put forth by the physician Rudolf Virchow (1821-1903), who wrote: "Between animal and man there is no dividing line---nor should there be. The object is different but the experience obtained constitutes the basis of all medicine."
Personalized medicine involves tailoring cancer treatment and prevention to the specific molecular nature of the individual and their cancer. The hope is that targeted therapies will be more effective with less risk for the patient than traditional treatments.
Animal Cancer Care and Research (ACCR) members from the University of Minnesota were key participants in a recently completed clinical trial testing a gene therapy approach to treat canine osteosarcoma.
Ear problems can cause a great deal of discomfort for dogs. So let's get to the bottom of the problem to understand what you can do to help your dog.
Dr. Nancy Kay give advice on keeping your dog's teeth healthy and clean.
Not all dogs come into contact with Leptospirosis. Dr. Nancy Kay discusses how to determine if you should vaccinate your dog for not Leptospirosis.
The AKC Canine Health Foundation (CHF) and our corporate alliance, Zoetis, are pleased to bring you another installment in a podcast series devoted to canine reproduction education for pet owners, breeders, and veterinarians.
In this podcast we discuss fresh chilled semen breeding, focusing on the stud dog. This podcast features Dr. Scarlette Gotwals, of Country Companion Animal Hospital in Morgantown Pennsylvania. Dr. Gotwals received her DVM from The Ohio State University in 1987. She has a special interest in canine reproduction and has been involved with canine reproduction and semen cryopreservation for 21 years. She is a nationally recognized authority in these areas and serves as a consultant to veterinarians through the Veterinarian Information Network. Dr. Gotwals is a consultant for the Canine Reproduction Division of Zoetis.
In June, part two of this podcast will be released, fresh chilled semen breeding, focusing on the bitch.