Hemangiosarcoma Research: AKC Match Initiative


In 2018, the AKC will generously match all donations made in support of canine hemangiosarcoma research, up to $250,000.

Donate to Hemangiosarcoma Research

What is Hemangiosarcoma?

  • An aggressive and common cancer in dogs.
  • While the cause of the disease is unknown, certain breeds (Golden Retriever, Portuguese Water Dog, Boxer, German Shepherd Dog) are considered to be high-risk. This suggests that heritable traits, while not singularly responsible, may contribute to the disease.
  • Hemangiosarcoma can develop in any tissue or organ, but the most common primary sites for these tumors include spleen, right atrium of the heart, and the skin.

Why study it?

  • While cutaneous masses (affecting the skin) are often treatable by tumor excision, tumors affecting internal organs are associated with poorer prognosis and are almost always incurable.
  • Hemangiosarcoma is often called the “silent killer” because the tumors are often not detected until the later stages of the disease, and even dogs harboring large tumors may show no clinical signs or evidence that they have a life threatening disease.
  • Because treatments have not improved the overall survival times for dogs with this disease, tremendous efforts are being made through research funded by the CHF and its donors to gain a better understanding of the biology and progression of this disease with the goal to design new and effective approaches to treatment.

CHF Studies:

02217: A Novel Mechanism to Regulate the Growth of Canine Hemangiosarcoma
Principal Investigator: Dr. Erin B. Dickerson, PhD; University of Minnesota
Total Grant Amount: $86,206.00; Grant Period: 1/1/2016 - 6/30/2018

02234-MOU: A Novel Approach for Prevention of Canine Hemangiosarcoma
Principal Investigator: Dr. Jaime F Modiano, VMD, PhD; University of Minnesota
Total Grant Amount: $432,000.00; Grant Period: 3/1/2016 - 2/28/2019

02519: Prevalence of Bartonella spp. Infection in Dogs with Cardiac and Splenic Hemangiosarcomas within and between Geographic Locations
Principal Investigator: Dr. Edward B Breitschwerdt, DVM; Matthew Breen, PhD; North Carolina State University
Total Grant Amount: $219,026.00; Grant Period: 2/1/2018 - 1/31/2020

02510: Identification of Novel Synthetic Lethal Partners to Optimize PI3K Targeted Therapies in Canine Hemangiosarcoma
Principal Investigator: Dr. Cheryl A. London, DVM PhD; Tufts Medical Center
Total Grant Amount: $168,857; Grant Period: 3/1/2018 - 2/28/2021

Publications on Hemangiosarcoma from CHF Studies:


Prevention Strategies for Canine Hemangiosarcoma?

See what Douglas H. Thamm, VMD, DACVIM (Oncology) has to say about cancer prevention as well as what we know about the connection between the use of vaccines, flea, tick and heartworm preventatives and cancer risk in dogs.

Update on Canine Hemangiosarcoma

Dr. Douglas H. Thamm, VMD, DACVIM (Oncology) presents on:

  •     The clinical presentation, staging, therapy and prognosis in canine hemangiosarcoma
  •     Recent findings about the biology of the disease
  •     Early diagnosis and new treatment strategies

Thank you to the sponsors of the Hemangiosarcoma Initiative!

Champion Sponsors ($50,000+)




Sponsors ($2,500+)

American Belgian Tervuren Club, Inc.
American Pointer Club
Australian Shepherd Health & Genetics Institute, Inc.
Australian Terrier Trust
Briard Club of America Health & Education Trust
Health & Rescue Foundation of the Petit Basset Griffon Vendeen Club of America
Irish Setter Club of America Foundation, Inc.
Rottweiler Health Foundation
Saluki Health Research, Inc.
Soft Coated Wheaten Terrier Club of America Endowment, Inc.
Weimaraner Foundation Fund Corporation

Help Future Generations of Dogs

Participate in canine health research by providing samples or by enrolling in a clinical trial. Samples are needed from healthy dogs and dogs affected by specific diseases.

Learn How to Help

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